CHEBI:60584 - bicozamycin

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ChEBI Name bicozamycin
ChEBI ID CHEBI:60584
Definition A commercially important azabicyclic antibiotic obtained from Streptomyces sapporonensis. It inhibits the Rho protein of E. coli.
Stars This entity has been manually annotated by the ChEBI Team.
Submitter Jane Lomax
Secondary ChEBI IDs CHEBI:3091
Supplier Information
Download Molfile XML SDF
Formula C12H18N2O7
Net Charge 0
Average Mass 302.28050
Monoisotopic Mass 302.11140
InChI InChI=1S/C12H18N2O7/c1-6-3-4-21-12(7(16)10(2,19)5-15)9(18)13-11(6,20)8(17)14-12/h7,15-16,19-20H,1,3-5H2,2H3,(H,13,18)(H,14,17)/t7-,10-,11+,12-/m0/s1
InChIKey WOUDXEYYJPOSNE-VKZDFBPFSA-N
SMILES C[C@](O)(CO)[C@H](O)[C@@]12NC(=O)[C@@](O)(NC1=O)C(=C)CCO2
Roles Classification
Biological Role(s): antibacterial agent
A substance (or active part thereof) that kills or slows the growth of bacteria.
Application(s): antiinfective agent
A substance used in the prophylaxis or therapy of infectious diseases.
antidiarrhoeal drug
Any drug found useful in the symptomatic treatment of diarrhoea.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing bicozamycin (CHEBI:60584) has role antibacterial agent (CHEBI:33282)
bicozamycin (CHEBI:60584) has role antidiarrhoeal drug (CHEBI:55323)
bicozamycin (CHEBI:60584) has role antiinfective agent (CHEBI:35441)
bicozamycin (CHEBI:60584) is a azabicycloalkane (CHEBI:38295)
bicozamycin (CHEBI:60584) is a bridged compound (CHEBI:35990)
IUPAC Name
(1S,6R)-6-hydroxy-5-methylidene-1-[(1S,2S)-1,2,3-trihydroxy-2-methylpropyl]-2-oxa-7,9-diazabicyclo[4.2.2]decane-8,10-dione
INNs Sources
bicozamicina ChemIDplus
bicozamycin ChemIDplus
bicozamycine ChemIDplus
bicozamycinum ChemIDplus
Synonyms Sources
aizumycin SUBMITTER
Bicozamycin KEGG COMPOUND
Bicyclomycin KEGG COMPOUND
Manual Xrefs Databases
C00018850 KNApSAcK
C11259 KEGG COMPOUND
View more database links
Registry Numbers Types Sources
38129-37-2 CAS Registry Number KEGG COMPOUND
38129-37-2 CAS Registry Number ChemIDplus
566286 Reaxys Registry Number Reaxys
Last Modified
04 August 2014