CHEBI:59782 - diphemanil methylsulfate

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ChEBI Name diphemanil methylsulfate
ChEBI ID CHEBI:59782
Definition The alkene resulting from the formal Wittig olefination of benzophenone and 1,1-dimethyl-4-bromopiperidinium methylsulfate. A quaternary ammonium anticholinergic, it binds muscarinic acetycholine receptors and thereby decreases secretory excretion of stomach acids, saliva and sweat, It is used topically in the treatment of hyperhidorsis (excessive sweating).
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C21H27NO4S
Net Charge 0
Average Mass 389.50800
Monoisotopic Mass 389.166
InChI InChI=1S/C20H24N.CH4O4S/c1-21(2)15-13-19(14-16-21)20(17-9-5-3-6-10-17)18-11-7-4-8-12-18;1-5-6(2,3)4/h3-12H,13-16H2,1-2H3;1H3,(H,2,3,4)/q+1;/p-1
InChIKey BREMLQBSKCSNNH-UHFFFAOYSA-M
SMILES COS([O-])(=O)=O.C[N+]1(C)CCC(CC1)=C(c1ccccc1)c1ccccc1
Roles Classification
Biological Role(s): muscarinic antagonist
A drug that binds to but does not activate muscarinic cholinergic receptors, thereby blocking the actions of endogenous acetylcholine or exogenous agonists.
parasympatholytic
Any cholinergic antagonist that inhibits the actions of the parasympathetic nervous system. The major group of drugs used therapeutically for this purpose is the muscarinic antagonists.
Application(s): muscarinic antagonist
A drug that binds to but does not activate muscarinic cholinergic receptors, thereby blocking the actions of endogenous acetylcholine or exogenous agonists.
parasympatholytic
Any cholinergic antagonist that inhibits the actions of the parasympathetic nervous system. The major group of drugs used therapeutically for this purpose is the muscarinic antagonists.
bronchodilator agent
An agent that causes an increase in the expansion of a bronchus or bronchial tubes.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing diphemanil methylsulfate (CHEBI:59782) has role bronchodilator agent (CHEBI:35523)
diphemanil methylsulfate (CHEBI:59782) has role muscarinic antagonist (CHEBI:48876)
diphemanil methylsulfate (CHEBI:59782) has role parasympatholytic (CHEBI:50370)
diphemanil methylsulfate (CHEBI:59782) is a piperidines (CHEBI:26151)
diphemanil methylsulfate (CHEBI:59782) is a quaternary ammonium salt (CHEBI:35273)
IUPAC Name
4-(diphenylmethylidene)-1,1-dimethylpiperidinium methyl sulfate
INNs Sources
diphemanil methylsulfate ChemIDplus
diphemanili metilsulfas ChemIDplus
metilsulfate de diphemanil ChemIDplus
metilsulfato de difemanilo ChemIDplus
Synonyms Sources
4-(diphenylmethylene)-1,1-dimethylpiperidinium methyl sulfate ChemIDplus
diphemanil methosulfate ChemIDplus
diphemanil metilsulfate ChEBI
N,N-dimethyl-4-piperidylidene-1,1-diphenylmethane methylsulfate ChEBI
p-(α-phenylbenzylidene)-1,1-dimethylpiperidinium methyl sulfate ChemIDplus
Database Links Databases
D06878 KEGG DRUG
DB00729 DrugBank
Diphemanil Wikipedia
US2739968 Patent
View more database links
Registry Numbers Types Sources
3842254 Beilstein Registry Number Beilstein
62-97-5 CAS Registry Number ChemIDplus
62-97-5 CAS Registry Number KEGG DRUG
Last Modified
19 July 2010