A secondary alcohol that is cyclohexanol substituted by two methyl groups at the 3-position and one methyl group at the 5-position. It exhibits inhibitory activity against HMG-CoA reductase ( EC 188.8.131.52/EC 184.108.40.206).
This entity has been manually annotated by the ChEBI Team.
Any EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD+ or NADP+ acceptor) inhibitor that inhibits HMG-CoA reductases. Hydroxymethylglutaryl-CoA reductase inhibitors have been shown to lower directly cholesterol synthesis. The Enzyme Commission designation is EC 220.127.116.11 for the NADPH-dependent enzyme and EC 18.104.22.168 for an NADH-dependent enzyme.