CHEBI:59062 - polymyxin

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name polymyxin
Definition Polymyxins are antibiotics with a general structure consisting of a cyclic peptide with a long hydrophobic tail. They disrupt the structure of the bacterial cell membrane by interacting with its phospholipids. Polymyxins are produced by the Gram-positive bacterium Bacillus polymyxa and are selectively toxic for Gram-negative bacteria.
Stars This entity has been manually annotated by the ChEBI Team.
Roles Classification
Chemical Role(s): Bronsted base
A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
(via organic amino compound )
Biological Role(s): antibacterial agent
A substance (or active part thereof) that kills or slows the growth of bacteria.
antimicrobial agent
A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing polymyxin (CHEBI:59062) has role antibacterial agent (CHEBI:33282)
polymyxin (CHEBI:59062) has role antimicrobial agent (CHEBI:33281)
polymyxin (CHEBI:59062) is a heterodetic cyclic peptide (CHEBI:24533)
polymyxin (CHEBI:59062) is a lipopeptide (CHEBI:46895)
Incoming colistimethate (CHEBI:59662) is a polymyxin (CHEBI:59062)
colistimethate A (CHEBI:59669) is a polymyxin (CHEBI:59062)
colistimethate B (CHEBI:59671) is a polymyxin (CHEBI:59062)
colistimethate sodium (CHEBI:34650) is a polymyxin (CHEBI:59062)
colistin (CHEBI:37943) is a polymyxin (CHEBI:59062)
colistin A (CHEBI:59064) is a polymyxin (CHEBI:59062)
colistin A sodium methanesulfonate (CHEBI:59663) is a polymyxin (CHEBI:59062)
colistin B (CHEBI:59673) is a polymyxin (CHEBI:59062)
colistin B sodium methanesulfonate (CHEBI:59664) is a polymyxin (CHEBI:59062)
polymyxin B1 (CHEBI:8309) is a polymyxin (CHEBI:59062)
polymyxin B2 (CHEBI:59063) is a polymyxin (CHEBI:59062)
Synonyms Sources
polymixin ChEBI
polymycin ChEBI
polymyxins ChEBI
Last Modified
17 June 2015