CHEBI:57451 - dihydrofolate(2−)

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ChEBI Name dihydrofolate(2−)
ChEBI ID CHEBI:57451
ChEBI ASCII Name dihydrofolate(2-)
Definition Dianion of dihydrofolic acid arising from deprotonation of both carboxylic acid functions.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Formula C19H19N7O6
Net Charge -2
Average Mass 441.39750
Monoisotopic Mass 441.14078
InChI InChI=1S/C19H21N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,12,21H,5-8H2,(H,24,29)(H,27,28)(H,31,32)(H4,20,22,25,26,30)/p-2/t12-/m0/s1
InChIKey OZRNSSUDZOLUSN-LBPRGKRZSA-L
SMILES Nc1nc2NCC(CNc3ccc(cc3)C(=O)N[C@@H](CCC([O-])=O)C([O-])=O)=Nc2c(=O)[nH]1
Metabolite of Species Details
Saccharomyces cerevisiae (NCBI:txid4932) Source: yeast.sf.net See: PubMed
Homo sapiens (NCBI:txid9606) See: DOI
Roles Classification
Biological Role(s): Saccharomyces cerevisiae metabolite
Any fungal metabolite produced during a metabolic reaction in Baker's yeast (Saccharomyces cerevisiae ).
human metabolite
Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens).
View more via ChEBI Ontology
ChEBI Ontology
Outgoing dihydrofolate(2−) (CHEBI:57451) has role Saccharomyces cerevisiae metabolite (CHEBI:75772)
dihydrofolate(2−) (CHEBI:57451) has role human metabolite (CHEBI:77746)
dihydrofolate(2−) (CHEBI:57451) is a dicarboxylic acid dianion (CHEBI:28965)
dihydrofolate(2−) (CHEBI:57451) is a dihydrofolates (CHEBI:67014)
dihydrofolate(2−) (CHEBI:57451) is conjugate base of dihydrofolic acid (CHEBI:15633)
Incoming dihydrofolic acid (CHEBI:15633) is conjugate acid of dihydrofolate(2−) (CHEBI:57451)
IUPAC Name
N-(4-{[(2-amino-4-oxo-3,4,7,8-tetrahydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamate
Synonyms Sources
7,8-dihydrofolate UniProt
dihydrofolate dianion ChEBI
Last Modified
21 January 2016