CHEBI:53770 - aceprometazine

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ChEBI Name aceprometazine
ChEBI ID CHEBI:53770
Definition A phenothiazine compound having an acetyl group at the 2-position and a 2-(dimethylamino)-1-propyl group at the 10-position.
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C19H22N2OS
Net Charge 0
Average Mass 326.45600
Monoisotopic Mass 326.145
InChI InChI=1S/C19H22N2OS/c1-13(20(3)4)12-21-16-7-5-6-8-18(16)23-19-10-9-15(14(2)22)11-17(19)21/h5-11,13H,12H2,1-4H3
InChIKey XLOQNFNTQIRSOX-UHFFFAOYSA-N
SMILES CC(CN1c2ccccc2Sc2ccc(cc12)C(C)=O)N(C)C
Roles Classification
Biological Role(s): histamine antagonist
Histamine antagonists are the drugs that bind to but do not activate histamine receptors, thereby blocking the actions of histamine or histamine agonists.
Application(s): anxiolytic drug
Anxiolytic drugs are agents that alleviate anxiety, tension, and anxiety disorders, promote sedation, and have a calming effect without affecting clarity of consciousness or neurologic conditions.
sedative
A central nervous system depressant used to induce drowsiness or sleep or to reduce psychological excitement or anxiety.
histamine antagonist
Histamine antagonists are the drugs that bind to but do not activate histamine receptors, thereby blocking the actions of histamine or histamine agonists.
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ChEBI Ontology
Outgoing aceprometazine (CHEBI:53770) has role anxiolytic drug (CHEBI:35474)
aceprometazine (CHEBI:53770) has role histamine antagonist (CHEBI:37956)
aceprometazine (CHEBI:53770) has role sedative (CHEBI:35717)
aceprometazine (CHEBI:53770) is a aromatic ketone (CHEBI:76224)
aceprometazine (CHEBI:53770) is a methyl ketone (CHEBI:51867)
aceprometazine (CHEBI:53770) is a phenothiazines (CHEBI:38093)
aceprometazine (CHEBI:53770) is a tertiary amine (CHEBI:32876)
Incoming (R)-aceprometazine (CHEBI:53771) is a aceprometazine (CHEBI:53770)
(S)-aceprometazine (CHEBI:53772) is a aceprometazine (CHEBI:53770)
IUPAC Name
1-{10-[2-(dimethylamino)propyl]-10H-phenothiazin-2-yl}ethanone
INNs Sources
aceprometazina DrugBank
acéprométazine WHO MedNet
aceprometazine DrugBank
aceprometazinum DrugBank
Synonyms Sources
10-(2-(Dimethylamino)propyl)phenothiazin-2-yl methyl ketone ChEBI
Acepromethazine ChemIDplus
Database Links Databases
50 DrugCentral
Aceprometazine Wikipedia
DB01615 DrugBank
View more database links
Registry Numbers Types Sources
13461-01-3 CAS Registry Number DrugBank
13461-01-3 CAS Registry Number ChemIDplus
13461-01-3 CAS Registry Number NIST Chemistry WebBook
38528 Reaxys Registry Number Reaxys
38528 Beilstein Registry Number Beilstein
Last Modified
22 February 2017