CHEBI:518413 - alverine

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ChEBI Name alverine
ChEBI ID CHEBI:518413
Definition A tertiary amine having one ethyl and two 3-phenylprop-1-yl groups attached to the nitrogen. An antispasmodic that acts directly on intestinal and uterine smooth muscle, it is used (particularly as the citrate salt) in the treatment of irritable bowel syndrome.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
Download Molfile XML SDF
Formula C20H27N
Net Charge 0
Average Mass 281.43510
Monoisotopic Mass 281.214
InChI InChI=1S/C20H27N/c1-2-21(17-9-15-19-11-5-3-6-12-19)18-10-16-20-13-7-4-8-14-20/h3-8,11-14H,2,9-10,15-18H2,1H3
InChIKey ZPFXAOWNKLFJDN-UHFFFAOYSA-N
SMILES CCN(CCCc1ccccc1)CCCc1ccccc1
Roles Classification
Chemical Role(s): Bronsted base
A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
(via organic amino compound )
Application(s): antispasmodic drug
A drug that suppresses spasms. These are usually caused by smooth muscle contraction, especially in tubular organs. The effect is to prevent spasms of the stomach, intestine or urinary bladder.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing alverine (CHEBI:518413) has role antispasmodic drug (CHEBI:53784)
alverine (CHEBI:518413) is a tertiary amine (CHEBI:32876)
alverine (CHEBI:518413) is conjugate base of alverine(1+) (CHEBI:64320)
Incoming alverine(1+) (CHEBI:64320) is conjugate acid of alverine (CHEBI:518413)
IUPAC Name
N-ethyl-3-phenyl-N-(3-phenylpropyl)propan-1-amine
INNs Sources
alverina DrugBank
alverine KEGG DRUG
alverinum DrugBank
Synonyms Sources
Bis(gamma-phenylpropyl)ethylamine DrugBank
Di(phenylpropyl)ethylamine DrugBank
N,N-Bis(3-phenylpropyl)ethylamine ChemIDplus
N-Ethyl-3,3'-diphenyldipropylamine DrugBank
N-Ethyl-3-phenyl-N-(3-phenylpropyl)-1-propanamine NIST Chemistry WebBook
N-Ethyl-N-(3-phenylpropyl)benzenepropanamine DrugBank
Phenopropamine DrugBank
Phenpropamine DrugBank
Manual Xrefs Databases
142 DrugCentral
D07440 KEGG DRUG
DB01616 DrugBank
LSM-3988 LINCS
View more database links
Registry Numbers Types Sources
150-59-4 CAS Registry Number ChemIDplus
150-59-4 CAS Registry Number NIST Chemistry WebBook
150-59-4 CAS Registry Number KEGG DRUG
2856783 Beilstein Registry Number Beilstein
Last Modified
22 February 2017