CHEBI:50949 - serotonin uptake inhibitor

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ChEBI Name serotonin uptake inhibitor
ChEBI ID CHEBI:50949
Definition A compound that specifically inhibits the reuptake of serotonin in the brain. This increases the serotonin concentration in the synaptic cleft which then activates serotonin receptors to a greater extent.
Stars This entity has been manually annotated by the ChEBI Team.
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ChEBI Ontology
Outgoing serotonin uptake inhibitor (CHEBI:50949) is a serotonergic drug (CHEBI:48278)
Incoming (R)-fluoxetine (CHEBI:86991) has role serotonin uptake inhibitor (CHEBI:50949)
(R)-fluoxetine hydrochloride (CHEBI:86996) has role serotonin uptake inhibitor (CHEBI:50949)
(R,R)-tramadol (CHEBI:75725) has role serotonin uptake inhibitor (CHEBI:50949)
(R,R)-tramadol hydrochloride (CHEBI:75733) has role serotonin uptake inhibitor (CHEBI:50949)
(S)-fenfluramine (CHEBI:439329) has role serotonin uptake inhibitor (CHEBI:50949)
(S)-fenfluramine hydrochloride (CHEBI:59730) has role serotonin uptake inhibitor (CHEBI:50949)
(S)-fluoxetine (CHEBI:86992) has role serotonin uptake inhibitor (CHEBI:50949)
(S)-fluoxetine hydrochloride (CHEBI:86997) has role serotonin uptake inhibitor (CHEBI:50949)
(S,S)-tramadol (CHEBI:75731) has role serotonin uptake inhibitor (CHEBI:50949)
(S,S)-tramadol hydrochloride (CHEBI:75734) has role serotonin uptake inhibitor (CHEBI:50949)
amoxapine (CHEBI:2675) has role serotonin uptake inhibitor (CHEBI:50949)
chlorphenamine (CHEBI:52010) has role serotonin uptake inhibitor (CHEBI:50949)
citalopram (CHEBI:3723) has role serotonin uptake inhibitor (CHEBI:50949)
citalopram hydrobromide (CHEBI:3724) has role serotonin uptake inhibitor (CHEBI:50949)
clomipramine (CHEBI:47780) has role serotonin uptake inhibitor (CHEBI:50949)
cocaine (CHEBI:27958) has role serotonin uptake inhibitor (CHEBI:50949)
desipramine (CHEBI:47781) has role serotonin uptake inhibitor (CHEBI:50949)
escitalopram hydrobromide (CHEBI:77423) has role serotonin uptake inhibitor (CHEBI:50949)
fenfluramine (CHEBI:5000) has role serotonin uptake inhibitor (CHEBI:50949)
fenfluramine hydrochloride (CHEBI:59729) has role serotonin uptake inhibitor (CHEBI:50949)
fluoxetine (CHEBI:5118) has role serotonin uptake inhibitor (CHEBI:50949)
fluoxetine hydrochloride (CHEBI:5119) has role serotonin uptake inhibitor (CHEBI:50949)
fluvoxamine (CHEBI:5138) has role serotonin uptake inhibitor (CHEBI:50949)
minaprine (CHEBI:51038) has role serotonin uptake inhibitor (CHEBI:50949)
nefazodone (CHEBI:7494) has role serotonin uptake inhibitor (CHEBI:50949)
nefopam (CHEBI:88316) has role serotonin uptake inhibitor (CHEBI:50949)
nefopam hydrochloride (CHEBI:88312) has role serotonin uptake inhibitor (CHEBI:50949)
olanzapine (CHEBI:7735) has role serotonin uptake inhibitor (CHEBI:50949)
paroxetine (CHEBI:7936) has role serotonin uptake inhibitor (CHEBI:50949)
paroxetine maleate (CHEBI:64194) has role serotonin uptake inhibitor (CHEBI:50949)
sertraline (CHEBI:9123) has role serotonin uptake inhibitor (CHEBI:50949)
sertraline hydrochloride (CHEBI:9124) has role serotonin uptake inhibitor (CHEBI:50949)
sibutramine (CHEBI:9137) has role serotonin uptake inhibitor (CHEBI:50949)
tramadol (CHEBI:9648) has role serotonin uptake inhibitor (CHEBI:50949)
tramadol hydrochloride (CHEBI:32250) has role serotonin uptake inhibitor (CHEBI:50949)
trazodone (CHEBI:9654) has role serotonin uptake inhibitor (CHEBI:50949)
trazodone hydrochloride (CHEBI:9655) has role serotonin uptake inhibitor (CHEBI:50949)
venlafaxine (CHEBI:9943) has role serotonin uptake inhibitor (CHEBI:50949)
vilazodone (CHEBI:70707) has role serotonin uptake inhibitor (CHEBI:50949)
vilazodone hydrochloride (CHEBI:70705) has role serotonin uptake inhibitor (CHEBI:50949)
Synonyms Sources
serotonin reuptake inhibitor ChEBI
SSRI ChEBI
Manual Xref Database
Selective_serotonin_reuptake_inhibitor Wikipedia
View more database links
Last Modified
22 October 2015