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InChI=1S/CH4O/c1-2/h2H,1H3
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ChEBI
> Main
CHEBI:50841 - loxapine
Main
ChEBI Ontology
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ChEBI Name
loxapine
ChEBI ID
CHEBI:50841
Stars
This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs
CHEBI:50839, CHEBI:6548
Supplier Information
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Formula
C18H18ClN3O
Net Charge
0
Average Mass
327.80784
Monoisotopic Mass
327.11384
InChI
InChI=1S/C18H18ClN3O/c1-
21-
8-
10-
22(11-
9-
21)
18-
14-
12-
13(19)
6-
7-
16(14)
23-
17-
5-
3-
2-
4-
15(17)
20-
18/h2-
7,12H,8-
11H2,1H3
InChIKey
XJGVXQDUIWGIRW-UHFFFAOYSA-N
SMILES
CN1CCN(CC1)C1=Nc2ccccc2Oc2ccc(Cl)cc12
Roles Classification
Biological Role
(s):
dopaminergic antagonist
A drug that binds to but does not activate dopamine receptors, thereby blocking the actions of dopamine or exogenous agonists.
Application
(s):
antipsychotic agent
Antipsychotic drugs are agents that control agitated psychotic behaviour, alleviate acute psychotic states, reduce psychotic symptoms, and exert a quieting effect.
dopaminergic antagonist
A drug that binds to but does not activate dopamine receptors, thereby blocking the actions of dopamine or exogenous agonists.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing
loxapine (
CHEBI:50841
)
has role
antipsychotic agent (
CHEBI:35476
)
loxapine (
CHEBI:50841
)
has role
dopaminergic antagonist (
CHEBI:48561
)
loxapine (
CHEBI:50841
)
is a
dibenzooxazepine (
CHEBI:53802
)
Incoming
loxapine succinate (
CHEBI:6549
)
has part
loxapine (
CHEBI:50841
)
IUPAC Name
2-chloro-11-(4-methylpiperazin-1-yl)dibenzo[
b
,
f
][1,4]oxazepine
INNs
Sources
loxapina
ChemIDplus
loxapine
ChemIDplus
loxapinum
ChemIDplus
Synonyms
Sources
2-chloro-11-(4-methyl-1-piperazinyl)dibenz[
b
,
f
][1,4]oxazepine
NIST Chemistry WebBook
Loxapine
KEGG COMPOUND
oxilapine
ChemIDplus
Brand Name
Source
Cloxazepine
DrugBank
Manual Xrefs
Databases
1613
DrugCentral
C07104
KEGG COMPOUND
D02340
KEGG DRUG
DB00408
DrugBank
Loxapine
Wikipedia
LSM-2881
LINCS
NL6406089
Patent
US3412193
Patent
US3546226
Patent
View more database links
Registry Numbers
Types
Sources
1977-10-2
CAS Registry Number
KEGG COMPOUND
1977-10-2
CAS Registry Number
ChemIDplus
1977-10-2
CAS Registry Number
NIST Chemistry WebBook
626753
Beilstein Registry Number
Beilstein
Last Modified
22 February 2017