CHEBI:47612 - bezafibrate

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ChEBI Name bezafibrate
ChEBI ID CHEBI:47612
Definition A monocarboxylic acid amide obtained by the formal condensation of the carboxy group of 4-chlorobenzoic acid with the amino group of 2-[4-(2-aminoethyl)phenoxy]-2-methylpropanoic acid. Benafibrate is used for the treatment of hyperlipidaemia.
Stars This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs CHEBI:47611, CHEBI:31284
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Formula C19H20ClNO4
Net Charge 0
Average Mass 361.81914
Monoisotopic Mass 361.108
InChI InChI=1S/C19H20ClNO4/c1-19(2,18(23)24)25-16-9-3-13(4-10-16)11-12-21-17(22)14-5-7-15(20)8-6-14/h3-10H,11-12H2,1-2H3,(H,21,22)(H,23,24)
InChIKey IIBYAHWJQTYFKB-UHFFFAOYSA-N
SMILES CC(C)(Oc1ccc(CCNC(=O)c2ccc(Cl)cc2)cc1)C(O)=O
Roles Classification
Chemical Role(s): environmental contaminant
Any minor or unwanted substance introduced into the environment that can have undesired effects.
Bronsted acid
A molecular entity capable of donating a hydron to an acceptor (Bronsted base).
(via oxoacid )
Biological Role(s): xenobiotic
A xenobiotic (Greek, xenos "foreign"; bios "life") is a compound that is foreign to a living organism. Principal xenobiotics include: drugs, carcinogens and various compounds that have been introduced into the environment by artificial means.
Application(s): antilipemic drug
A substance used to treat hyperlipidemia (an excess of lipids in the blood).
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ChEBI Ontology
Outgoing bezafibrate (CHEBI:47612) has functional parent propionic acid (CHEBI:30768)
bezafibrate (CHEBI:47612) has role antilipemic drug (CHEBI:35679)
bezafibrate (CHEBI:47612) has role environmental contaminant (CHEBI:78298)
bezafibrate (CHEBI:47612) has role xenobiotic (CHEBI:35703)
bezafibrate (CHEBI:47612) is a aromatic ether (CHEBI:35618)
bezafibrate (CHEBI:47612) is a monocarboxylic acid (CHEBI:25384)
bezafibrate (CHEBI:47612) is a monocarboxylic acid amide (CHEBI:29347)
bezafibrate (CHEBI:47612) is a monochlorobenzenes (CHEBI:83403)
IUPAC Name
2-{4-[2-(4-chlorobenzamido)ethyl]phenoxy}-2-methylpropanoic acid
INNs Sources
bezafibrate ChemIDplus
bezafibrato DrugBank
bezafibratum DrugBank
Synonyms Sources
2-(p-(2-(p-Chlorobenzamido)ethyl)phenoxy)-2-methylpropionic acid ChemIDplus
Bezatol SR (TN) KEGG DRUG
Cedur ChEBI
Brand Names Sources
Befizal DrugBank
Bezalip DrugBank
Manual Xrefs Databases
362 DrugCentral
Bezafibrate Wikipedia
D01366 KEGG DRUG
DB01393 DrugBank
DE2149070 Patent
HMDB0015465 HMDB
LSM-3015 LINCS
PEM PDBeChem
US3781328 Patent
View more database links
Registry Numbers Types Sources
41859-67-0 CAS Registry Number ChemIDplus
41859-67-0 CAS Registry Number KEGG DRUG
4267656 Reaxys Registry Number Reaxys
Citations Waiting for Citations Types Sources
17379010 PubMed citation Europe PMC
18787029 PubMed citation Europe PMC
19131462 PubMed citation Europe PMC
Last Modified
22 February 2017
General Comments
2014-05-07 Bezafibrate can be found in blood and urine samples of individuals who have taken this drug.
2014-10-29 Stravs M, Schymanski E, Singer H, Department of Environmental Chemistry, Eawag