CHEBI:473992 - nystatin A1

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ChEBI Name nystatin A1
ChEBI ASCII Name nystatin A1
Definition A polyene macrolide antibiotic; part of the nystatin complex produced by several Streptomyces species. It is an antifungal antibiotic used for the treatment of topical fungal infections caused by a broad spectrum of fungal pathogens comprising yeast-like and filamentous species.
Stars This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs CHEBI:31926
Supplier Information
Download Molfile XML SDF
Formula C47H75NO17
Net Charge 0
Average Mass 926.107
Monoisotopic Mass 925.50350
InChI InChI=1S/C47H75NO17/c1-27-17-15-13-11-9-7-5-6-8-10-12-14-16-18-34(64-46-44(58)41(48)43(57)30(4)63-46)24-38-40(45(59)60)37(54)26-47(61,65-38)25-36(53)35(52)20-19-31(49)21-32(50)22-33(51)23-39(55)62-29(3)28(2)42(27)56/h5-6,8,10-18,27-38,40-44,46,49-54,56-58,61H,7,9,19-26,48H2,1-4H3,(H,59,60)/b6-5+,10-8+,13-11+,14-12+,17-15+,18-16+/t27-,28-,29-,30+,31+,32+,33+,34-,35+,36+,37-,38-,40+,41-,42+,43+,44-,46-,47+/m0/s1
SMILES [H][C@]12C[C@@H](O[C@@H]3O[C@H](C)[C@@H](O)[C@H](N)[C@@H]3O)\C=C\C=C\C=C\C=C\CC\C=C\C=C\[C@H](C)[C@@H](O)[C@@H](C)[C@H](C)OC(=O)C[C@H](O)C[C@H](O)C[C@H](O)CC[C@@H](O)[C@H](O)C[C@](O)(C[C@H](O)[C@H]1C(O)=O)O2
Metabolite of Species Details
Streptomyces noursei (NCBI:txid1971) See: DOI
Streptomyces sp. HSG2 (NCBI:txid2797167) See: PubMed
Amycolatopsis aidingensis (NCBI:txid2842453) Species also known as Amycolatopsis sp. YIM 96748. See: PubMed
Streptomyces ahygroscopicus (NCBI:txid387846) See: PubMed
Roles Classification
Chemical Role(s): Bronsted acid
A molecular entity capable of donating a hydron to an acceptor (Bronsted base).
(via oxoacid )
Biological Role(s): bacterial metabolite
Any prokaryotic metabolite produced during a metabolic reaction in bacteria.
(via nystatins )
antimicrobial agent
A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans.
(via macrolide antibiotic )
(via carbohydrate-containing antibiotic )
antifungal drug
Any antifungal agent used to prevent or treat fungal infections in humans or animals.
(via antibiotic antifungal drug )
antifungal agent
An antimicrobial agent that destroys fungi by suppressing their ability to grow or reproduce.
(via antibiotic antifungal agent )
Application(s): antifungal drug
Any antifungal agent used to prevent or treat fungal infections in humans or animals.
(via antibiotic antifungal drug )
View more via ChEBI Ontology
ChEBI Ontology
Outgoing nystatin A1 (CHEBI:473992) is a nystatins (CHEBI:59676)
Incoming nystatin (CHEBI:7660) has part nystatin A1 (CHEBI:473992)
(1S,3R,4R,7R,9R,11R,15S,16R,17R,18S,19E,21E,25E,27E,29E,31E,33R,35S,36R,37S)-33-[(3-amino-3,6-dideoxy-β-D-mannopyranosyl)oxy]-1,3,4,7,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,25,27,29,31-hexaene-36-carboxylic acid
Synonym Source
nystatin A1 LIPID MAPS
Manual Xrefs Databases
2985 VSDB
HMDB0242564 HMDB
View more database links
Registry Numbers Types Sources
12153125 Beilstein Registry Number Beilstein
34786-70-4 CAS Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
1086913 PubMed citation Europe PMC
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Last Modified
18 August 2022