CHEBI:4653 - dipyridamole

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ChEBI Name dipyridamole
Definition A pyrimidopyrimidine that is 2,2',2'',2'''-(pyrimido[5,4-d]pyrimidine-2,6-diyldinitrilo)tetraethanol substituted by piperidin-1-yl groups at positions 4 and 8 respectively. A vasodilator agent, it inhibits the formation of blood clots.
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C24H40N8O4
Net Charge 0
Average Mass 504.62592
Monoisotopic Mass 504.31725
InChI InChI=1S/C24H40N8O4/c33-15-11-31(12-16-34)23-26-20-19(21(27-23)29-7-3-1-4-8-29)25-24(32(13-17-35)14-18-36)28-22(20)30-9-5-2-6-10-30/h33-36H,1-18H2
Roles Classification
Chemical Role(s): Bronsted base
A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
(via organic amino compound )
Biological Role(s): adenosine phosphodiesterase inhibitor

EC (adenosine deaminase) inhibitor
An EC 3.5.4.* (non-peptide cyclic amidine C-N hydrolase) inhibitor that interferes with the action of adenosine deaminase (EC
Application(s): platelet aggregation inhibitor
A drug or agent which antagonizes or impairs any mechanism leading to blood platelet aggregation, whether during the phases of activation and shape change or following the dense-granule release reaction and stimulation of the prostaglandin-thromboxane system.
vasodilator agent
A drug used to cause dilation of the blood vessels.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing dipyridamole (CHEBI:4653) has role adenosine phosphodiesterase inhibitor (CHEBI:50444)
dipyridamole (CHEBI:4653) has role EC (adenosine deaminase) inhibitor (CHEBI:50445)
dipyridamole (CHEBI:4653) has role platelet aggregation inhibitor (CHEBI:50427)
dipyridamole (CHEBI:4653) has role vasodilator agent (CHEBI:35620)
dipyridamole (CHEBI:4653) is a piperidines (CHEBI:26151)
dipyridamole (CHEBI:4653) is a pyrimidopyrimidine (CHEBI:48514)
dipyridamole (CHEBI:4653) is a tertiary amino compound (CHEBI:50996)
dipyridamole (CHEBI:4653) is a tetrol (CHEBI:33573)
INNs Sources
dipyridamole ChemIDplus
dipyridamolum ChemIDplus
Synonyms Sources
Dipyridamine DrugBank
Dipyudamine DrugBank
Dypyridamol DrugBank
Brand Names Sources
Cardoxin ChEBI
Cleridium 150 DrugBank
Curantyl DrugBank
dipiridamol ChemIDplus
Persantin DrugBank
Manual Xrefs Databases
924 DrugCentral
DB00975 DrugBank
Dipyridamole Wikipedia
GB807826 Patent
US3031450 Patent
View more database links
Registry Numbers Types Sources
0068373 Beilstein Registry Number Beilstein
58-32-2 CAS Registry Number ChemIDplus
68373 Reaxys Registry Number Reaxys
Citations Waiting for Citations Types Sources
11098344 PubMed citation Europe PMC
11709364 PubMed citation Europe PMC
Last Modified
22 February 2017