CHEBI:465284 - ganciclovir

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name ganciclovir
ChEBI ID CHEBI:465284
Definition An oxopurine that is guanine substituted by a [(1,3-dihydroxypropan-2-yl)oxy]methyl group at position 9. Ganciclovir is an antiviral drug used to treat or prevent AIDS-related cytomegalovirus infections.
Stars This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs CHEBI:42659, CHEBI:5273
Supplier Information
Download Molfile XML SDF
more structures >>
Wikipedia License
Waiting for wikipedia content
Read full article at Wikipedia
Formula C9H13N5O4
Net Charge 0
Average Mass 255.23060
Monoisotopic Mass 255.097
InChI InChI=1S/C9H13N5O4/c10-9-12-7-6(8(17)13-9)11-3-14(7)4-18-5(1-15)2-16/h3,5,15-16H,1-2,4H2,(H3,10,12,13,17)
InChIKey IRSCQMHQWWYFCW-UHFFFAOYSA-N
SMILES Nc1nc2n(COC(CO)CO)cnc2c(=O)[nH]1
Roles Classification
Biological Role(s): antiviral drug
A substance used in the prophylaxis or therapy of virus diseases.
Application(s): antiviral drug
A substance used in the prophylaxis or therapy of virus diseases.
antiinfective agent
A substance used in the prophylaxis or therapy of infectious diseases.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing ganciclovir (CHEBI:465284) has functional parent guanine (CHEBI:16235)
ganciclovir (CHEBI:465284) has role antiinfective agent (CHEBI:35441)
ganciclovir (CHEBI:465284) has role antiviral drug (CHEBI:36044)
ganciclovir (CHEBI:465284) is a 2-aminopurines (CHEBI:20702)
ganciclovir (CHEBI:465284) is a oxopurine (CHEBI:25810)
Incoming valganciclovir (CHEBI:63635) has functional parent ganciclovir (CHEBI:465284)
IUPAC Name
2-amino-9-{[(1,3-dihydroxypropan-2-yl)oxy]methyl}-1,9-dihydro-6H-purin-6-one
INN Source
ganciclovir KEGG DRUG
Synonyms Sources
2-(6-Amino-purin-9-ylmethoxy)-propane-1,3-diol ChEMBL
2-amino-9-((1,3-dihydroxypropan-2-yloxy)methyl)-1H-purin-6(9H)-one ChEMBL
2-amino-9-((1,3-dihydroxypropan-2-yloxy)methyl)-3H-purin-6(9H)-one ChEMBL
2-amino-9-((1,3-dihydroxypropan-2-yloxy)methyl)-9H-purin-6-ol ChEMBL
2-Amino-9-(2-hydroxy-1-hydroxymethyl-ethoxymethyl)-1,9-dihydro-purin-6-one ChEMBL
2-amino-9-(2-hydroxy-1-hydroxymethylethoxymethyl)-6,9-dihydro-1H-6-purinone ChEMBL
9-((2-Hydroxy-1-(hydroxymethyl)ethoxy)methyl)guanine ChemIDplus
9-(1,3-DIHYDROXY-PROPOXYMETHANE)GUANINE PDBeChem
9-[(1,3-dihydroxy-2-propoxy)methyl]guanine ChEMBL
GA2 DrugBank
Ganciclovir KEGG COMPOUND
ganciclovirum ChemIDplus
gancyclovir ChEMBL
Manual Xrefs Databases
1277 DrugCentral
D00333 KEGG DRUG
DB01004 DrugBank
GA2 PDBeChem
Ganciclovir Wikipedia
HMDB0015139 HMDB
LSM-5382 LINCS
US4355032 Patent
View more database links
Registry Numbers Types Sources
3654487 Beilstein Registry Number Beilstein
3654487 Reaxys Registry Number Reaxys
82410-32-0 CAS Registry Number KEGG COMPOUND
82410-32-0 CAS Registry Number DrugBank
82410-32-0 CAS Registry Number KEGG DRUG
82410-32-0 CAS Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
10197958 PubMed citation ChEMBL
10377226 PubMed citation ChEMBL
10411487 PubMed citation ChEMBL
10447945 PubMed citation ChEMBL
10560739 PubMed citation ChEMBL
10691698 PubMed citation ChEMBL
10882370 PubMed citation ChEMBL
10882372 PubMed citation ChEMBL
10882374 PubMed citation ChEMBL
10882375 PubMed citation ChEMBL
10888336 PubMed citation ChEMBL
10966740 PubMed citation ChEMBL
10966745 PubMed citation ChEMBL
10999475 PubMed citation ChEMBL
11229780 PubMed citation ChEMBL
11262090 PubMed citation ChEMBL
11412988 PubMed citation ChEMBL
11454465 PubMed citation ChEMBL
11472207 PubMed citation ChEMBL
11495586 PubMed citation ChEMBL
11585457 PubMed citation ChEMBL
11677126 PubMed citation ChEMBL
11708924 PubMed citation ChEMBL
11708929 PubMed citation ChEMBL
11754587 PubMed citation ChEMBL
11814776 PubMed citation ChEMBL
11858989 PubMed citation ChEMBL
11985471 PubMed citation ChEMBL
12408716 PubMed citation ChEMBL
12459010 PubMed citation ChEMBL
12723951 PubMed citation ChEMBL
1310744 PubMed citation ChEMBL
1319491 PubMed citation ChEMBL
1323678 PubMed citation ChEMBL
14521407 PubMed citation ChEMBL
14584954 PubMed citation ChEMBL
14643328 PubMed citation ChEMBL
14643358 PubMed citation ChEMBL
14736238 PubMed citation ChEMBL
15027877 PubMed citation ChEMBL
15081019 PubMed citation ChEMBL
15481985 PubMed citation ChEMBL
15509173 PubMed citation ChEMBL
15509174 PubMed citation ChEMBL
15509175 PubMed citation ChEMBL
15509176 PubMed citation ChEMBL
15615545 PubMed citation ChEMBL
15634003 PubMed citation ChEMBL
15658858 PubMed citation ChEMBL
15658861 PubMed citation ChEMBL
15658873 PubMed citation ChEMBL
15689173 PubMed citation ChEMBL
15745823 PubMed citation ChEMBL
15801851 PubMed citation ChEMBL
16134946 PubMed citation ChEMBL
16392791 PubMed citation ChEMBL
16392824 PubMed citation ChEMBL
16420056 PubMed citation ChEMBL
16480257 PubMed citation ChEMBL
1652016 PubMed citation ChEMBL
16759112 PubMed citation ChEMBL
16814545 PubMed citation ChEMBL
17004726 PubMed citation ChEMBL
17043128 PubMed citation ChEMBL
17092728 PubMed citation ChEMBL
17161946 PubMed citation ChEMBL
17181158 PubMed citation ChEMBL
17181162 PubMed citation ChEMBL
17188402 PubMed citation ChEMBL
17239594 PubMed citation ChEMBL
17298047 PubMed citation ChEMBL
17329103 PubMed citation ChEMBL
17402726 PubMed citation ChEMBL
17434304 PubMed citation ChEMBL
17438061 PubMed citation ChEMBL
17513108 PubMed citation ChEMBL
17518459 PubMed citation ChEMBL
17539622 PubMed citation ChEMBL
17622128 PubMed citation ChEMBL
17672445 PubMed citation ChEMBL
17869124 PubMed citation ChEMBL
17948980 PubMed citation ChEMBL
17960926 PubMed citation ChEMBL
18082410 PubMed citation ChEMBL
1849998 PubMed citation ChEMBL
2157013 PubMed citation ChEMBL
2160539 PubMed citation ChEMBL
2163453 PubMed citation ChEMBL
2163454 PubMed citation ChEMBL
2165163 PubMed citation ChEMBL
2175356 PubMed citation ChEMBL
2329551 PubMed citation ChEMBL
2329561 PubMed citation ChEMBL
2391689 PubMed citation ChEMBL
2500527 PubMed citation ChEMBL
2544723 PubMed citation ChEMBL
2822928 PubMed citation ChEMBL
2826784 PubMed citation ChEMBL
2840500 PubMed citation ChEMBL
2842505 PubMed citation ChEMBL
2846837 PubMed citation ChEMBL
2848125 PubMed citation ChEMBL
2913300 PubMed citation ChEMBL
2989523 PubMed citation ChEMBL
2993615 PubMed citation ChEMBL
3009811 PubMed citation ChEMBL
3016263 PubMed citation ChEMBL
3871860 PubMed citation ChEMBL
7562929 PubMed citation ChEMBL
7562946 PubMed citation ChEMBL
7562947 PubMed citation ChEMBL
7752205 PubMed citation ChEMBL
7877148 PubMed citation ChEMBL
7932543 PubMed citation ChEMBL
8071942 PubMed citation ChEMBL
8176714 PubMed citation ChEMBL
8254613 PubMed citation ChEMBL
8394933 PubMed citation ChEMBL
8632412 PubMed citation ChEMBL
8709116 PubMed citation ChEMBL
8765514 PubMed citation ChEMBL
8784444 PubMed citation ChEMBL
8784445 PubMed citation ChEMBL
8941388 PubMed citation ChEMBL
9046339 PubMed citation ChEMBL
9057866 PubMed citation ChEMBL
9057867 PubMed citation ChEMBL
9057868 PubMed citation ChEMBL
9216836 PubMed citation ChEMBL
9438017 PubMed citation ChEMBL
9548814 PubMed citation ChEMBL
9575044 PubMed citation ChEMBL
9836613 PubMed citation ChEMBL
9836626 PubMed citation ChEMBL
9871553 PubMed citation ChEMBL
9925738 PubMed citation ChEMBL
9934470 PubMed citation ChEMBL
9934471 PubMed citation ChEMBL
Last Modified
22 February 2017