CHEBI:46024 - trichostatin A

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name trichostatin A
Stars This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs CHEBI:39145, CHEBI:46022
Supplier Information
Download Molfile XML SDF
more structures >>
Wikipedia License
Waiting for wikipedia content
Read full article at Wikipedia
Formula C17H22N2O3
Net Charge 0
Average Mass 302.36826
Monoisotopic Mass 302.16304
InChI InChI=1S/C17H22N2O3/c1-12(5-10-16(20)18-22)11-13(2)17(21)14-6-8-15(9-7-14)19(3)4/h5-11,13,22H,1-4H3,(H,18,20)/b10-5+,12-11+/t13-/m1/s1
SMILES C[C@@H](C(=O)c1ccc(cc1)N(C)C)\C=C(C)\C=C\C(=O)NO
Metabolite of Species Details
Streptomyces hygroscopicus (NCBI:txid1912) See: PubMed
Roles Classification
Biological Role(s): bacterial metabolite
Any prokaryotic metabolite produced during a metabolic reaction in bacteria.
EC (histone deacetylase) inhibitor
An EC 3.5.1.* (non-peptide linear amide C-N hydrolase) inhibitor that interferes with the function of histone deacetylase (EC
antifungal agent
An antimicrobial agent that destroys fungi by suppressing their ability to grow or reproduce.
(via antibiotic antifungal agent )
antimicrobial agent
A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans.
(via carbocyclic antibiotic )
Application(s): geroprotector
Any compound that supports healthy aging, slows the biological aging process, or extends lifespan.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing trichostatin A (CHEBI:46024) has functional parent (R)-trichostatic acid (CHEBI:39158)
trichostatin A (CHEBI:46024) has role bacterial metabolite (CHEBI:76969)
trichostatin A (CHEBI:46024) has role EC (histone deacetylase) inhibitor (CHEBI:61115)
trichostatin A (CHEBI:46024) has role geroprotector (CHEBI:176497)
trichostatin A (CHEBI:46024) is a antibiotic antifungal agent (CHEBI:86478)
trichostatin A (CHEBI:46024) is a hydroxamic acid (CHEBI:24650)
trichostatin A (CHEBI:46024) is a trichostatin (CHEBI:39146)
Incoming trichostatin C (CHEBI:39147) has functional parent trichostatin A (CHEBI:46024)
trichostatin D (CHEBI:39160) has functional parent trichostatin A (CHEBI:46024)
Synonyms Sources
(2E,4E,6R)-7-(4-(dimethylamino)phenyl)-N-hydroxy-4,6-dimethyl-7-oxo-2,4-heptadienamide ChemIDplus
TSA ChemIDplus
Manual Xrefs Databases
C00016002 KNApSAcK
DB04297 DrugBank
HMDB0259177 HMDB
Trichostatin_A Wikipedia
View more database links
Registry Numbers Types Sources
5291761 Beilstein Registry Number Beilstein
58880-19-6 CAS Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
10490031 PubMed citation Europe PMC
15346199 PubMed citation Europe PMC
16010430 PubMed citation Europe PMC
18285338 PubMed citation Europe PMC
19038231 PubMed citation Europe PMC
21504214 PubMed citation Europe PMC
25075551 PubMed citation Europe PMC
27454931 PubMed citation Europe PMC
30395713 PubMed citation Europe PMC
31755702 PubMed citation Europe PMC
32880591 PubMed citation Europe PMC
33983895 PubMed citation Europe PMC
34086940 PubMed citation Europe PMC
Last Modified
27 October 2021