CHEBI:41922 - diethylstilbestrol

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ChEBI Name diethylstilbestrol
Definition An olefinic compound that is trans-hex-3-ene in which the hydrogens at positions 3 and 4 have been replaced by p-hydroxyphenyl groups.
Stars This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs CHEBI:4531, CHEBI:41920
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Formula C18H20O2
Net Charge 0
Average Mass 268.35020
Monoisotopic Mass 268.14633
InChI InChI=1S/C18H20O2/c1-3-17(13-5-9-15(19)10-6-13)18(4-2)14-7-11-16(20)12-8-14/h5-12,19-20H,3-4H2,1-2H3/b18-17+
SMILES CC\C(c1ccc(O)cc1)=C(\CC)c1ccc(O)cc1
Roles Classification
Biological Role(s): carcinogenic agent
A role played by a chemical compound which is known to induce a process of carcinogenesis by corrupting normal cellular pathways, leading to the acquistion of tumoral capabilities.
antifungal agent
An antimicrobial agent that destroys fungi by suppressing their ability to grow or reproduce.
EC (11beta-hydroxysteroid dehydrogenase) inhibitor
An EC 1.1.1.* (oxidoreductase acting on donor CH-OH group, NAD+ or NADP+ acceptor) inhibitor that interferes with the action of 11beta-hydroxysteroid dehydrogenase (EC
autophagy inducer
Any compound that induces the process of autophagy (the self-digestion of one or more components of a cell through the action of enzymes originating within the same cell).
calcium channel blocker
One of a class of drugs that acts by selective inhibition of calcium influx through cell membranes or on the release and binding of calcium in intracellular pools.
A synthetic or semi-synthetic compound that has oestrogenic activity.
EC (H(+)/K(+)-exchanging ATPase) inhibitor
An EC 3.6.3.* (acid anhydride hydrolase catalysing transmembrane movement of substances) inhibitor that inhibits H+/K+-exchanging ATPase, EC Such compounds are also known as proton pump inhibitors.
Application(s): antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
endocrine disruptor
Any compound that can disrupt the functions of the endocrine (hormone) system
A synthetic or semi-synthetic compound that has oestrogenic activity.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing diethylstilbestrol (CHEBI:41922) has role antifungal agent (CHEBI:35718)
diethylstilbestrol (CHEBI:41922) has role antineoplastic agent (CHEBI:35610)
diethylstilbestrol (CHEBI:41922) has role autophagy inducer (CHEBI:138880)
diethylstilbestrol (CHEBI:41922) has role calcium channel blocker (CHEBI:38215)
diethylstilbestrol (CHEBI:41922) has role carcinogenic agent (CHEBI:50903)
diethylstilbestrol (CHEBI:41922) has role EC (11β-hydroxysteroid dehydrogenase) inhibitor (CHEBI:137626)
diethylstilbestrol (CHEBI:41922) has role EC (H+/K+-exchanging ATPase) inhibitor (CHEBI:49200)
diethylstilbestrol (CHEBI:41922) has role endocrine disruptor (CHEBI:138015)
diethylstilbestrol (CHEBI:41922) has role xenoestrogen (CHEBI:76988)
diethylstilbestrol (CHEBI:41922) is a olefinic compound (CHEBI:78840)
diethylstilbestrol (CHEBI:41922) is a polyphenol (CHEBI:26195)
Incoming diethylstilbestrol diphosphate (CHEBI:4532) has functional parent diethylstilbestrol (CHEBI:41922)
INNs Sources
diéthylstilbestrol ChEBI
diethylstilbestrol ChemIDplus
diethylstilbestrolum ChemIDplus
dietilestilbestrol ChemIDplus
Synonyms Sources
(E)-3,4-bis(4-hydroxyphenyl)-3-hexene ChemIDplus
(E)-4,4'-(1,2-diethyl-1,2-ethenediyl)bisphenol NIST Chemistry WebBook
4,4'-dihydroxy-α,β-diethylstilbene NIST Chemistry WebBook
α,α'-diethyl-(E)-4,4'-stilbenediol NIST Chemistry WebBook
Diethylstilbestrol KEGG COMPOUND
trans-4,4'-(1,2-diethyl-1,2-ethenediyl)bisphenol NIST Chemistry WebBook
trans-Diethylstilbesterol DrugBank
trans-Diethylstilbestrol DrugBank
trans-Diethylstilboesterol DrugBank
Brand Name Source
Distilbene DrugBank
Manual Xrefs Databases
875 DrugCentral
DB00255 DrugBank
Diethylstilbestrol Wikipedia
FDB007498 FooDB
HMDB0014400 HMDB
View more database links
Registry Numbers Types Sources
2056095 Beilstein Registry Number ChemIDplus
56-53-1 CAS Registry Number ChemIDplus
56-53-1 CAS Registry Number NIST Chemistry WebBook
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Last Modified
04 November 2019