CHEBI:3814 - colestipol

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ChEBI Name colestipol
Definition A high molecular weight copolymer of diethylenetriamine and epichlorohydrin (hydrochloride), with approximately 1 out of 5 amine nitrogens protonated. Due to the highly cross-linked and insoluble nature of the material, no structural formula has been assigned and no specific molecular weight information is available. A basic anion exchange resin, it is used as its hydrochloride for binding bile acids in the intestine, inhibiting their reabsorption.
Stars This entity has been manually annotated by the ChEBI Team.
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Roles Classification
Chemical Role(s): Bronsted base
A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
(via organic amino compound )
Application(s): anticholesteremic drug
A substance used to lower plasma cholesterol levels.
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ChEBI Ontology
Outgoing colestipol (CHEBI:3814) has role anticholesteremic drug (CHEBI:35821)
colestipol (CHEBI:3814) is a copolymer macromolecule (CHEBI:53310)
colestipol (CHEBI:3814) is a polyamine macromolecule (CHEBI:51349)
Incoming colestipol hydrochloride (CHEBI:59602) has part colestipol (CHEBI:3814)
INN Source
colestipolum ChemIDplus
Synonym Source
Manual Xrefs Databases
DB00375 DrugBank
US3692895 Patent
US3803237 Patent
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Registry Numbers Types Sources
26658-42-4 CAS Registry Number KEGG COMPOUND
50925-79-6 CAS Registry Number ChemIDplus
9896237 Beilstein Registry Number Beilstein
Last Modified
04 August 2014