CHEBI:3651 - chlorprothixene

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name chlorprothixene
ChEBI ID CHEBI:3651
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
Download Molfile XML SDF
Formula C18H18ClNS
Net Charge 0
Average Mass 315.86000
Monoisotopic Mass 315.08485
InChI InChI=1S/C18H18ClNS/c1-20(2)11-5-7-14-15-6-3-4-8-17(15)21-18-10-9-13(19)12-16(14)18/h3-4,6-10,12H,5,11H2,1-2H3
InChIKey WSPOMRSOLSGNFJ-UHFFFAOYSA-N
SMILES [H]C(CCN(C)C)=C1c2ccccc2Sc2ccc(Cl)cc12
Roles Classification
Chemical Role(s): Bronsted base
A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
(via organic amino compound )
Biological Role(s): non-narcotic analgesic
A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors.
cholinergic antagonist
Any drug that binds to but does not activate cholinergic receptors, thereby blocking the actions of acetylcholine or cholinergic agonists.
dopaminergic antagonist
A drug that binds to but does not activate dopamine receptors, thereby blocking the actions of dopamine or exogenous agonists.
Application(s): non-narcotic analgesic
A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors.
antiemetic
A drug used to prevent nausea or vomiting. An antiemetic may act by a wide range of mechanisms: it might affect the medullary control centres (the vomiting centre and the chemoreceptive trigger zone) or affect the peripheral receptors.
sedative
A central nervous system depressant used to induce drowsiness or sleep or to reduce psychological excitement or anxiety.
cholinergic antagonist
Any drug that binds to but does not activate cholinergic receptors, thereby blocking the actions of acetylcholine or cholinergic agonists.
dopaminergic antagonist
A drug that binds to but does not activate dopamine receptors, thereby blocking the actions of dopamine or exogenous agonists.
first generation antipsychotic
Antipsychotic drugs which can have different modes of action but which tend to be more likely than second generation antipsychotics to cause extrapyramidal motor control disabilities such as body rigidity or Parkinson's disease-type movements; such body movements can become permanent even after treatment has ceased.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing chlorprothixene (CHEBI:3651) has role antiemetic (CHEBI:50919)
chlorprothixene (CHEBI:3651) has role cholinergic antagonist (CHEBI:48873)
chlorprothixene (CHEBI:3651) has role dopaminergic antagonist (CHEBI:48561)
chlorprothixene (CHEBI:3651) has role first generation antipsychotic (CHEBI:65190)
chlorprothixene (CHEBI:3651) has role non-narcotic analgesic (CHEBI:35481)
chlorprothixene (CHEBI:3651) has role sedative (CHEBI:35717)
chlorprothixene (CHEBI:3651) is a tertiary amine (CHEBI:32876)
chlorprothixene (CHEBI:3651) is a thioxanthenes (CHEBI:50930)
Incoming (Z)-chlorprothixene (CHEBI:50931) has functional parent chlorprothixene (CHEBI:3651)
IUPAC Name
3-(2-chloro-9H-thioxanthen-9-ylidene)-N,N-dimethylpropan-1-amine
INNs Sources
chlorprothixène ChEBI
chlorprothixene ChEBI
chlorprothixenum ChEBI
clorprotixeno ChEBI
Synonyms Sources
Alpha-Chlorprothixene DrugBank
Chlorprothixen DrugBank
Chlorprothixene KEGG COMPOUND
Chlorprothixine DrugBank
Chlorprotixen DrugBank
Chlorprotixene DrugBank
Chlorprotixine DrugBank
Chlothixen DrugBank
Manual Xrefs Databases
C07953 KEGG COMPOUND
D00790 KEGG DRUG
DB01239 DrugBank
GB829763 Patent
LSM-3310 LINCS
US3046283 Patent
View more database links
Registry Numbers Types Sources
113-59-7 CAS Registry Number ChemIDplus
89898 Beilstein Registry Number Beilstein
Last Modified
25 February 2016