CHEBI:32215 - thiamphenicol

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name thiamphenicol
ChEBI ID CHEBI:32215
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
Download Molfile XML SDF
Formula C12H15Cl2NO5S
Net Charge 0
Average Mass 356.22264
Monoisotopic Mass 355.005
InChI InChI=1S/C12H15Cl2NO5S/c1-21(19,20)8-4-2-7(3-5-8)10(17)9(6-16)15-12(18)11(13)14/h2-5,9-11,16-17H,6H2,1H3,(H,15,18)/t9-,10-/m1/s1
InChIKey OTVAEFIXJLOWRX-NXEZZACHSA-N
SMILES CS(=O)(=O)c1ccc(cc1)[C@@H](O)[C@@H](CO)NC(=O)C(Cl)Cl
Roles Classification
Biological Role(s): antimicrobial agent
A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans.
immunosuppressive agent
An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response.
Application(s): immunosuppressive agent
An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing thiamphenicol (CHEBI:32215) has role antimicrobial agent (CHEBI:33281)
thiamphenicol (CHEBI:32215) has role immunosuppressive agent (CHEBI:35705)
thiamphenicol (CHEBI:32215) is a monocarboxylic acid amide (CHEBI:29347)
thiamphenicol (CHEBI:32215) is a sulfone (CHEBI:35850)
IUPAC Name
2,2-dichloro-N-{(1R,2R)-2-hydroxy-1-(hydroxymethyl)-2-[4-(methylsulfonyl)phenyl]ethyl}acetamide
Synonyms Sources
(+)-Thiamphenicol ChemIDplus
Armai (TN) KEGG DRUG
D-(+)-threo-2,2-Dichloro-N-(beta-hydroxy-alpha-(hydroxymethyl)-p-(methylsulfonyl)phenethyl)acetamide ChemIDplus
Thiamphenicol KEGG COMPOUND
Thiocymetin (TN) KEGG DRUG
Manual Xrefs Databases
1911 VSDB
2624 DrugCentral
C12853 KEGG COMPOUND
D01407 KEGG DRUG
DB08621 DrugBank
LSM-5858 LINCS
TH8 PDBeChem
View more database links
Registry Numbers Types Sources
15318-45-3 CAS Registry Number KEGG COMPOUND
15318-45-3 CAS Registry Number ChemIDplus
Last Modified
22 February 2017