CHEBI:31981 - periciazine

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name periciazine
Definition A member of the class of phenothiazines that is 10H-phenothiazine substituted by a 3-(4-hydroxypiperidin-1-yl)propyl group at the nitrogen atom and a carbonitrile group at position 2. Periciazine is a first generation antipsychotic.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
Download Molfile XML SDF
Wikipedia License
Waiting for wikipedia content
Read full article at Wikipedia
Formula C21H23N3OS
Net Charge 0
Average Mass 365.49294
Monoisotopic Mass 365.15618
InChI InChI=1S/C21H23N3OS/c22-15-16-6-7-21-19(14-16)24(18-4-1-2-5-20(18)26-21)11-3-10-23-12-8-17(25)9-13-23/h1-2,4-7,14,17,25H,3,8-13H2
SMILES OC1CCN(CCCN2c3ccccc3Sc3ccc(cc23)C#N)CC1
Roles Classification
Biological Role(s): adrenergic antagonist
An agent that binds to but does not activate adrenergic receptors thereby blocking the actions of endogenous or exogenous adrenergic agonists.
Application(s): adrenergic antagonist
An agent that binds to but does not activate adrenergic receptors thereby blocking the actions of endogenous or exogenous adrenergic agonists.
A central nervous system depressant used to induce drowsiness or sleep or to reduce psychological excitement or anxiety.
first generation antipsychotic
Antipsychotic drugs which can have different modes of action but which tend to be more likely than second generation antipsychotics to cause extrapyramidal motor control disabilities such as body rigidity or Parkinson's disease-type movements; such body movements can become permanent even after treatment has ceased.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing periciazine (CHEBI:31981) has parent hydride 10H-phenothiazine (CHEBI:37931)
periciazine (CHEBI:31981) has role adrenergic antagonist (CHEBI:37887)
periciazine (CHEBI:31981) has role first generation antipsychotic (CHEBI:65190)
periciazine (CHEBI:31981) has role sedative (CHEBI:35717)
periciazine (CHEBI:31981) is a hydroxypiperidine (CHEBI:48590)
periciazine (CHEBI:31981) is a nitrile (CHEBI:18379)
periciazine (CHEBI:31981) is a phenothiazines (CHEBI:38093)
INNs Sources
periciazina WHO MedNet
périciazine WHO MedNet
periciazine WHO MedNet
periciazinum WHO MedNet
Synonyms Sources
10-(3-(4-Hydroxypiperidino)propyl)phenothiazine-2-carbonitrile ChemIDplus
2-Cyano-10-(3-(4-hydroxy-1-piperidyl)propyl)phenothiazine ChemIDplus
2-Cyano-10-(3-(4-hydroxypiperidino)propyl)phenothiazine ChemIDplus
Cyano-3 ((hydroxy-4 piperidyl-1)-3 propyl)-10 phenothiazine ChemIDplus
Piperocyanomazine ChemIDplus
Propericiazine ChemIDplus
Manual Xrefs Databases
2107 DrugCentral
DB01608 DrugBank
FR1212031 Patent
HMDB0015546 HMDB
Periciazine Wikipedia
View more database links
Registry Numbers Types Sources
2622-26-6 CAS Registry Number ChemIDplus
576739 Reaxys Registry Number Reaxys
576739 Beilstein Registry Number Beilstein
Citations Waiting for Citations Types Sources
10441864 PubMed citation Europe PMC
16454538 PubMed citation Europe PMC
17606915 PubMed citation Europe PMC
27062 PubMed citation Europe PMC
5981335 PubMed citation Europe PMC
8562516 PubMed citation Europe PMC
9591093 PubMed citation Europe PMC
Last Modified
22 February 2017