CHEBI:31859 - modafinil

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name modafinil
Definition A racemate comprising equimolar amounts of armodafinil and (S)-modafinil. A central nervous system stimulant, it is used for the treatment of sleeping disorders such as narcolepsy, obstructive sleep apnoea, and shift-work sleep disorder. The optical enantiomers of modafinil have similar pharmacological actions in animals.
Stars This entity has been manually annotated by the ChEBI Team.
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Roles Classification
Application(s): central nervous system stimulant
Any drug that enhances the activity of the central nervous system.
A phsychotropic drug that improves wakefulness and alertness, and reduces tiredness, drowsiness, and the need for sleep. Eugeroics are relatively non-addictive and are used in the treatment of narcolepsy and other sleep disorders.
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ChEBI Ontology
Outgoing modafinil (CHEBI:31859) has part (S)-modafinil (CHEBI:77591)
modafinil (CHEBI:31859) has part armodafinil (CHEBI:77590)
modafinil (CHEBI:31859) has role central nervous system stimulant (CHEBI:35337)
modafinil (CHEBI:31859) has role eugeroic (CHEBI:77567)
modafinil (CHEBI:31859) is a racemate (CHEBI:60911)
INNs Sources
modafinil WHO MedNet
modafinil WHO MedNet
modafinilo WHO MedNet
modafinilum WHO MedNet
Synonyms Sources
(±)-modafinil ChemIDplus
2-(benzhydrylsulfinyl)acetamide ChemIDplus
CEP-1538 ChEBI
CRL 40476 ChemIDplus
CRL-40476 ChEBI
Brand Name Source
Provigil KEGG DRUG
Manual Xrefs Databases
DB00745 DrugBank
DE2809625 Patent
HMDB0014883 HMDB
Modafinil Wikipedia
US4177290 Patent
View more database links
Registry Numbers Types Sources
1978970 Reaxys Registry Number Reaxys
68693-11-8 CAS Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
17712350 PubMed citation Europe PMC
22537794 PubMed citation Europe PMC
23017017 PubMed citation Europe PMC
23261131 PubMed citation Europe PMC
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Last Modified
22 February 2017