CHEBI:3183 - brompheniramine

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ChEBI Name brompheniramine
ChEBI ID CHEBI:3183
Definition Pheniramine in which the hydrogen at position 4 of the phenyl substituent is substituted by bromine. A histamine H1 receptor antagonist, brompheniramine is used (commonly as its maleate salt) for the symptomatic relief of allergic conditions, including rhinitis and conjunctivitis.
Stars This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs CHEBI:154051
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Formula C16H19BrN2
Net Charge 0
Average Mass 319.23900
Monoisotopic Mass 318.073
InChI InChI=1S/C16H19BrN2/c1-19(2)12-10-15(16-5-3-4-11-18-16)13-6-8-14(17)9-7-13/h3-9,11,15H,10,12H2,1-2H3
InChIKey ZDIGNSYAACHWNL-UHFFFAOYSA-N
SMILES CN(C)CCC(c1ccc(Br)cc1)c1ccccn1
Roles Classification
Biological Role(s): H1-receptor antagonist
H1-receptor antagonists are the drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine.
Application(s): H1-receptor antagonist
H1-receptor antagonists are the drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine.
anti-allergic agent
A drug used to treat allergic reactions.
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ChEBI Ontology
Outgoing brompheniramine (CHEBI:3183) has role anti-allergic agent (CHEBI:50857)
brompheniramine (CHEBI:3183) has role H1-receptor antagonist (CHEBI:37955)
brompheniramine (CHEBI:3183) is a organobromine compound (CHEBI:37141)
brompheniramine (CHEBI:3183) is a pyridines (CHEBI:26421)
Incoming brompheniramine maleate (CHEBI:3184) has part brompheniramine (CHEBI:3183)
dexbrompheniramine (CHEBI:59269) is a brompheniramine (CHEBI:3183)
IUPAC Name
3-(4-bromophenyl)-N,N-dimethyl-3-(pyridin-2-yl)propan-1-amine
INNs Sources
bromfeniramina ChemIDplus
brompheniramine ChemIDplus
brompheniraminum ChemIDplus
Synonyms Sources
1-(p-bromophenyl)-1-(2-pyridyl)-3-dimethylaminopropane ChemIDplus
2-(p-bromo-α-(2-dimethylaminoethyl)benzyl)pyridine ChemIDplus
3-(4-bromophenyl)-N,N-dimethyl-3-(2-pyridinyl)-1-propanamine NIST Chemistry WebBook
3-(p-bromophenyl)-3-(2-pyridyl)-N,N-dimethylpropylamine ChemIDplus
[3-(4-Bromo-phenyl)-3-pyridin-2-yl-propyl]-dimethyl-amine ChEMBL
Brompheniramine KEGG COMPOUND
Manual Xrefs Databases
408 DrugCentral
Brompheniramine Wikipedia
C06857 KEGG COMPOUND
D07543 KEGG DRUG
DB00835 DrugBank
LSM-1736 LINCS
US2567245 Patent
US2676964 Patent
View more database links
Registry Numbers Types Sources
217066 Beilstein Registry Number Beilstein
86-22-6 CAS Registry Number ChemIDplus
86-22-6 CAS Registry Number NIST Chemistry WebBook
Citations Waiting for Citations Types Sources
2570152 PubMed citation ChEMBL
2579237 PubMed citation ChEMBL
6458703 PubMed citation ChEMBL
9526560 PubMed citation ChEMBL
Last Modified
22 February 2017