CHEBI:31783 - lornoxicam

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name lornoxicam
ChEBI ID CHEBI:31783
Definition A thienothiazine-derived monocarboxylic acid amide obtained by formal condensation of the carboxy group of 6-chloro-4-hydroxy-2-methylthieno[2,3-e][1,2]thiazine-3-carboxylic acid 1,1-dioxide with the amino group of 2-aminopyridine. Used for the treatment of pain, primarily resulting from inflammatory diseases of the joints, osteoarthritis, surgery, sciatica and other inflammations.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
Download Molfile XML SDF
Wikipedia License
Waiting for wikipedia content
Read full article at Wikipedia
Formula C13H10ClN3O4S2
Net Charge 0
Average Mass 371.81900
Monoisotopic Mass 370.980
InChI InChI=1S/C13H10ClN3O4S2/c1-17-10(13(19)16-9-4-2-3-5-15-9)11(18)12-7(23(17,20)21)6-8(14)22-12/h2-6,18H,1H3,(H,15,16,19)
InChIKey WLHQHAUOOXYABV-UHFFFAOYSA-N
SMILES CN1C(C(=O)Nc2ccccn2)=C(O)c2sc(Cl)cc2S1(=O)=O
Roles Classification
Biological Role(s): non-narcotic analgesic
A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors.
Application(s): non-steroidal anti-inflammatory drug
An anti-inflammatory drug that is not a steroid. In addition to anti-inflammatory actions, non-steroidal anti-inflammatory drugs have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins.
non-narcotic analgesic
A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors.
antipyretic
A drug that prevents or reduces fever by lowering the body temperature from a raised state. An antipyretic will not affect the normal body temperature if one does not have fever. Antipyretics cause the hypothalamus to override an interleukin-induced increase in temperature. The body will then work to lower the temperature and the result is a reduction in fever.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing lornoxicam (CHEBI:31783) has role antipyretic (CHEBI:35493)
lornoxicam (CHEBI:31783) has role non-narcotic analgesic (CHEBI:35481)
lornoxicam (CHEBI:31783) has role non-steroidal anti-inflammatory drug (CHEBI:35475)
lornoxicam (CHEBI:31783) is a heteroaryl hydroxy compound (CHEBI:74818)
lornoxicam (CHEBI:31783) is a monocarboxylic acid amide (CHEBI:29347)
lornoxicam (CHEBI:31783) is a organochlorine compound (CHEBI:36683)
lornoxicam (CHEBI:31783) is a pyridines (CHEBI:26421)
lornoxicam (CHEBI:31783) is a thienothiazine (CHEBI:46977)
IUPAC Name
6-chloro-4-hydroxy-2-methyl-N-(pyridin-2-yl)-2H-thieno[2,3-e][1,2]thiazine-3-carboxamide 1,1-dioxide
INNs Sources
lornoxicam WHO MedNet
lornoxicam WHO MedNet
lornoxicam KEGG DRUG
lornoxicamum DrugBank
Synonyms Sources
CCRIS 8589 ChemIDplus
Chlortenoxicam ChemIDplus
Ro 13-9297 ChemIDplus
Manual Xrefs Databases
1609 DrugCentral
D01866 KEGG DRUG
DB06725 DrugBank
Lornoxicam Wikipedia
US2008014272 Patent
View more database links
Registry Numbers Types Sources
1039965 Beilstein Registry Number ChemIDplus
1039965 Reaxys Registry Number Reaxys
70374-39-9 CAS Registry Number ChemIDplus
70374-39-9 CAS Registry Number KEGG DRUG
Citations Waiting for Citations Types Sources
21789617 PubMed citation Europe PMC
21968509 PubMed citation Europe PMC
22306394 PubMed citation Europe PMC
22459464 PubMed citation Europe PMC
22502750 PubMed citation Europe PMC
22545424 PubMed citation Europe PMC
22584689 PubMed citation Europe PMC
23215687 PubMed citation Europe PMC
23273940 PubMed citation Europe PMC
23385560 PubMed citation Europe PMC
23411533 PubMed citation Europe PMC
23428763 PubMed citation Europe PMC
23556534 PubMed citation Europe PMC
23567043 PubMed citation Europe PMC
23656309 PubMed citation Europe PMC
23657985 PubMed citation Europe PMC
23713572 PubMed citation Europe PMC
23781487 PubMed citation Europe PMC
23818079 PubMed citation Europe PMC
23827761 PubMed citation Europe PMC
23829186 PubMed citation Europe PMC
23884669 PubMed citation Europe PMC
23931243 PubMed citation Europe PMC
24029201 PubMed citation Europe PMC
Last Modified
22 February 2017