CHEBI:31749 - kebuzone

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ChEBI Name kebuzone
ChEBI ID CHEBI:31749
Definition A pyrazolidine that is phenylbutazone in which the two methylene hydrogens at postion 3 on the butyl chain are replaced by an oxo group.
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C19H18N2O3
Net Charge 0
Average Mass 322.35780
Monoisotopic Mass 322.13174
InChI InChI=1S/C19H18N2O3/c1-14(22)12-13-17-18(23)20(15-8-4-2-5-9-15)21(19(17)24)16-10-6-3-7-11-16/h2-11,17H,12-13H2,1H3
InChIKey LGYTZKPVOAIUKX-UHFFFAOYSA-N
SMILES CC(=O)CCC1C(=O)N(N(C1=O)c1ccccc1)c1ccccc1
Roles Classification
Biological Role(s): non-narcotic analgesic
A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors.
Application(s): non-steroidal anti-inflammatory drug
An anti-inflammatory drug that is not a steroid. In addition to anti-inflammatory actions, non-steroidal anti-inflammatory drugs have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins.
non-narcotic analgesic
A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors.
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ChEBI Ontology
Outgoing kebuzone (CHEBI:31749) has functional parent phenylbutazone (CHEBI:48574)
kebuzone (CHEBI:31749) has role non-narcotic analgesic (CHEBI:35481)
kebuzone (CHEBI:31749) has role non-steroidal anti-inflammatory drug (CHEBI:35475)
kebuzone (CHEBI:31749) is a methyl ketone (CHEBI:51867)
kebuzone (CHEBI:31749) is a pyrazolidines (CHEBI:38312)
INNs Sources
kébuzone WHO MedNet
kebuzone KEGG DRUG
kebuzonum ChemIDplus
quebuzona ChemIDplus
Synonyms Sources
1,2-Diphenyl-4-(gamma-ketobutyl)-3,5-pyrazolidinedione ChemIDplus
4-(3-Oxobutyl)-1,2-diphenyl-3,5-pyrazolidinedione ChemIDplus
Ketophenylbutazone KEGG DRUG
Ketophenylbutazonum ChemIDplus
Manual Xrefs Databases
1522 DrugCentral
D01567 KEGG DRUG
HMDB0041914 HMDB
Kebuzone Wikipedia
WO2007128412 Patent
View more database links
Registry Numbers Types Sources
308507 Reaxys Registry Number Reaxys
853-34-9 CAS Registry Number KEGG DRUG
853-34-9 CAS Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
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Last Modified
22 February 2017