CHEBI:31205 - amlexanox

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ChEBI Name amlexanox
Definition A pyridochromene-derived monocarboxylic acid having an amino substituent at the 2-position, an oxo substituent at the 5-position and an isopropyl substituent at the 7-position.
Stars This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs CHEBI:250549
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Formula C16H14N2O4
Net Charge 0
Average Mass 298.29340
Monoisotopic Mass 298.09536
InChI InChI=1S/C16H14N2O4/c1-7(2)8-3-4-12-9(5-8)13(19)10-6-11(16(20)21)14(17)18-15(10)22-12/h3-7H,1-2H3,(H2,17,18)(H,20,21)
SMILES CC(C)c1ccc2oc3nc(N)c(cc3c(=O)c2c1)C(O)=O
Roles Classification
Chemical Role(s): Bronsted acid
A molecular entity capable of donating a hydron to an acceptor (Bronsted base).
(via oxoacid )
Application(s): anti-allergic agent
A drug used to treat allergic reactions.
anti-ulcer drug
One of various classes of drugs with different action mechanisms used to treat or ameliorate peptic ulcer or irritation of the gastrointestinal tract.
non-steroidal anti-inflammatory drug
An anti-inflammatory drug that is not a steroid. In addition to anti-inflammatory actions, non-steroidal anti-inflammatory drugs have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins.
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ChEBI Ontology
Outgoing amlexanox (CHEBI:31205) has role anti-allergic agent (CHEBI:50857)
amlexanox (CHEBI:31205) has role anti-ulcer drug (CHEBI:49201)
amlexanox (CHEBI:31205) has role non-steroidal anti-inflammatory drug (CHEBI:35475)
amlexanox (CHEBI:31205) is a monocarboxylic acid (CHEBI:25384)
amlexanox (CHEBI:31205) is a pyridochromene (CHEBI:53792)
2-amino-5-oxo-7-(propan-2-yl)-5H-chromeno[2,3-b]pyridine-3-carboxylic acid
INNs Sources
amlexanox KEGG DRUG
amlexanoxo DrugBank
amlexanoxum DrugBank
Synonym Source
2-Amino-7-isopropyl-5-oxo-5H-(1)benzopyrano(2,3-b)pyridine-3-carboxylic acid ChemIDplus
Manual Xrefs Databases
182 DrugCentral
Amlexanox Wikipedia
DB01025 DrugBank
View more database links
Registry Numbers Types Sources
556384 Beilstein Registry Number Beilstein
68302-57-8 CAS Registry Number ChemIDplus
68302-57-8 CAS Registry Number DrugBank
68302-57-8 CAS Registry Number KEGG DRUG
Citations Waiting for Citations Types Sources
12873507 PubMed citation ChEMBL
3989816 PubMed citation ChEMBL
Last Modified
22 February 2017