CHEBI:3077 - betamethasone

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ChEBI Name betamethasone
ChEBI ID CHEBI:3077
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C22H29FO5
Net Charge 0
Average Mass 392.46110
Monoisotopic Mass 392.200
InChI InChI=1S/C22H29FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15-,16-,17-,19-,20-,21-,22-/m0/s1
InChIKey UREBDLICKHMUKA-DVTGEIKXSA-N
SMILES [H][C@@]12C[C@H](C)[C@](O)(C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]1(F)[C@@]2([H])CCC2=CC(=O)C=C[C@]12C
Roles Classification
Biological Role(s): immunosuppressive agent
An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response.
hormone
Originally referring to an endogenous compound that is formed in specialized organ or group of cells and carried to another organ or group of cells, in the same organism, upon which it has a specific regulatory function, the term is now commonly used to include non-endogenous, semi-synthetic and fully synthetic analogues of such compounds.
(via steroid hormone )
Application(s): anti-asthmatic agent
Any compound that has anti-asthmatic effects.
immunosuppressive agent
An agent that suppresses immune function by one of several mechanisms of action. Classical cytotoxic immunosuppressants act by inhibiting DNA synthesis. Others may act through activation of T-cells or by inhibiting the activation of helper cells. In addition, an immunosuppressive agent is a role played by a compound which is exhibited by a capability to diminish the extent and/or voracity of an immune response.
anti-inflammatory drug
A substance that reduces or suppresses inflammation.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing betamethasone (CHEBI:3077) has parent hydride pregnane (CHEBI:8386)
betamethasone (CHEBI:3077) has role anti-asthmatic agent (CHEBI:65023)
betamethasone (CHEBI:3077) has role anti-inflammatory drug (CHEBI:35472)
betamethasone (CHEBI:3077) has role immunosuppressive agent (CHEBI:35705)
betamethasone (CHEBI:3077) is a 11β-hydroxy steroid (CHEBI:35346)
betamethasone (CHEBI:3077) is a 17α-hydroxy steroid (CHEBI:35342)
betamethasone (CHEBI:3077) is a 20-oxo steroid (CHEBI:36885)
betamethasone (CHEBI:3077) is a 21-hydroxy steroid (CHEBI:35344)
betamethasone (CHEBI:3077) is a 3-oxo-Δ14-steroid (CHEBI:77166)
betamethasone (CHEBI:3077) is a fluorinated steroid (CHEBI:50830)
betamethasone (CHEBI:3077) is a glucocorticoid (CHEBI:24261)
betamethasone (CHEBI:3077) is a primary α-hydroxy ketone (CHEBI:139590)
betamethasone (CHEBI:3077) is a tertiary α-hydroxy ketone (CHEBI:139592)
Incoming betamethasone acetate (CHEBI:31275) has functional parent betamethasone (CHEBI:3077)
betamethasone acibutate (CHEBI:50894) has functional parent betamethasone (CHEBI:3077)
betamethasone dipropionate (CHEBI:31276) has functional parent betamethasone (CHEBI:3077)
betamethasone phosphate (CHEBI:68603) has functional parent betamethasone (CHEBI:3077)
betamethasone valerate (CHEBI:31277) has functional parent betamethasone (CHEBI:3077)
IUPAC Name
9-fluoro-11β,17,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione
INNs Sources
betametasona ChEBI
bétaméthasone ChEBI
betamethasone ChEBI
betamethasonum ChEBI
Synonyms Sources
16β-Methyl-1,4-pregnadiene-9α-fluoro-11β,17α,21-triol-3,20-dione ChemIDplus
9-Fluoro-16β-methylprednisolone ChemIDplus
9α-Fluoro-16β-methylprednisolone ChemIDplus
beta-Methasone alcohol ChemIDplus
Betadexamethasone ChemIDplus
Rinderon KEGG DRUG
Manual Xrefs Databases
1854 VSDB
348 DrugCentral
Betamethasone Wikipedia
D00244 KEGG DRUG
DB00443 DrugBank
US3053865 Patent
US3104246 Patent
View more database links
Registry Numbers Types Sources
3176546 Beilstein Registry Number Beilstein
378-44-9 CAS Registry Number NIST Chemistry WebBook
378-44-9 CAS Registry Number ChemIDplus
Last Modified
07 February 2018