CHEBI:30660 - thyroxine

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name thyroxine
ChEBI ID CHEBI:30660
Definition An iodothyronine compound having iodo substituents at the 3-, 3'-, 5- and 5'-positions.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
Download Molfile XML SDF
Formula C15H11I4NO4
Net Charge 0
Average Mass 776.87006
Monoisotopic Mass 776.687
InChI InChI=1S/C15H11I4NO4/c16-8-4-7(5-9(17)13(8)21)24-14-10(18)1-6(2-11(14)19)3-12(20)15(22)23/h1-2,4-5,12,21H,3,20H2,(H,22,23)
InChIKey XUIIKFGFIJCVMT-UHFFFAOYSA-N
SMILES NC(Cc1cc(I)c(Oc2cc(I)c(O)c(I)c2)c(I)c1)C(O)=O
Roles Classification
Chemical Role(s): Bronsted base
A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
(via organic amino compound )
Bronsted acid
A molecular entity capable of donating a hydron to an acceptor (Bronsted base).
(via oxoacid )
Biological Role(s): mitogen
A chemical substance that encourages a cell to commence cell division, triggering mitosis.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing thyroxine (CHEBI:30660) has role mitogen (CHEBI:52290)
thyroxine (CHEBI:30660) is a 2-halophenol (CHEBI:53291)
thyroxine (CHEBI:30660) is a iodophenol (CHEBI:24863)
thyroxine (CHEBI:30660) is a iodothyronine (CHEBI:24864)
thyroxine (CHEBI:30660) is a non-proteinogenic α-amino acid (CHEBI:83925)
thyroxine (CHEBI:30660) is a tyrosine derivative (CHEBI:62761)
thyroxine (CHEBI:30660) is tautomer of thyroxine zwitterion (CHEBI:305790)
Incoming thyroxine sulfate (CHEBI:53508) has functional parent thyroxine (CHEBI:30660)
D-thyroxine (CHEBI:30659) is a thyroxine (CHEBI:30660)
L-thyroxine (CHEBI:18332) is a thyroxine (CHEBI:30660)
thyroxine zwitterion (CHEBI:305790) is tautomer of thyroxine (CHEBI:30660)
IUPAC Name
thyroxine
Synonyms Sources
2-amino-3-[4-(4-hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]propanoic acid IUPAC
DL-Thyroxine ChemIDplus
O-(4-Hydroxy-3,5-diiodophenyl)-3,5-diiodo-DL-tyrosine ChemIDplus
Thx IUPAC
Registry Numbers Types Sources
2228514 Beilstein Registry Number Beilstein
300-30-1 CAS Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
15206581 PubMed citation Europe PMC
24375501 PubMed citation Europe PMC
9824273 PubMed citation Europe PMC
Last Modified
17 December 2014