CHEBI:29699 - tunicamycin

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name tunicamycin
ChEBI ID CHEBI:29699
Definition A mixture of antiviral nucleoside antibiotics produced by Streptomyces lysosuperificus. It contains at least 10 homologues comprising uracil, N-acetylglucosamine, an 11-carbon aminodialdose called tunicamine, and a fatty acid linked to the amino group of the tunicamine. The homologues vary in the composition of the fatty acid moiety.
Stars This entity has been manually annotated by the ChEBI Team.
Download Molfile XML SDF
Wikipedia License
Waiting for wikipedia content
Read full article at Wikipedia
Formula C25H38N4O16
Net Charge 0
Average Mass (excl. R groups) 650.587
Monoisotopic Mass (excl. R groups) 650.22828
SMILES [H][C@@](O)(C[C@H]1O[C@@H](OC2O[C@H]([*]O)[C@@H](O)[C@H](O)[C@H]2NC(C)=O)[C@H](NC([*])=O)[C@@H](O)[C@H]1O)[C@@]1([H])O[C@H]([C@H](O)[C@@H]1O)n1ccc(=O)[nH]c1=O
Roles Classification
Biological Role(s): antimicrobial agent
A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans.
EC 2.7.8.15 (UDP-N-acetylglucosamine--dolichyl-phosphate N-acetylglucosaminephosphotransferase) inhibitor
An EC 2.7.8.* (transferases for other substituted phosphate groups) inhibitor that interferes with the action of any UDP-N-acetylglucosaminedolichyl-phosphate N-acetylglucosaminephosphotransferase (EC 2.7.8.15), preventing formation of N-acetylglucosamine lipid intermediates and glycosylation of newly synthesised glycoproteins.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing tunicamycin (CHEBI:29699) has part tunicamycin A0 (CHEBI:64228)
tunicamycin (CHEBI:29699) has part tunicamycin A1 (CHEBI:64245)
tunicamycin (CHEBI:29699) has part tunicamycin A2 (CHEBI:64246)
tunicamycin (CHEBI:29699) has part tunicamycin B1 (CHEBI:64248)
tunicamycin (CHEBI:29699) has part tunicamycin B2 (CHEBI:64250)
tunicamycin (CHEBI:29699) has part tunicamycin B3 (CHEBI:64255)
tunicamycin (CHEBI:29699) has part tunicamycin C1 (CHEBI:64256)
tunicamycin (CHEBI:29699) has part tunicamycin C2 (CHEBI:64257)
tunicamycin (CHEBI:29699) has part tunicamycin D1 (CHEBI:64271)
tunicamycin (CHEBI:29699) has part tunicamycin D2 (CHEBI:64272)
tunicamycin (CHEBI:29699) has role antimicrobial agent (CHEBI:33281)
tunicamycin (CHEBI:29699) has role EC 2.7.8.15 (UDP-N-acetylglucosamine—dolichyl-phosphate N-acetylglucosaminephosphotransferase) inhibitor (CHEBI:64237)
tunicamycin (CHEBI:29699) is a mixture (CHEBI:60004)
Synonym Source
Tunicamycin KEGG COMPOUND
Manual Xrefs Databases
C12063 KEGG COMPOUND
Tunicamycin Wikipedia
View more database links
Registry Numbers Types Sources
11089-65-9 CAS Registry Number KEGG COMPOUND
11089-65-9 CAS Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
11478581 PubMed citation Europe PMC
11514096 PubMed citation Europe PMC
11732194 PubMed citation Europe PMC
11798249 PubMed citation Europe PMC
12093793 PubMed citation Europe PMC
12106388 PubMed citation Europe PMC
12136966 PubMed citation Europe PMC
12232600 PubMed citation Europe PMC
12232799 PubMed citation Europe PMC
12515321 PubMed citation Europe PMC
160437 PubMed citation Europe PMC
1624425 PubMed citation Europe PMC
3018444 PubMed citation Europe PMC
315774 PubMed citation Europe PMC
4624615 PubMed citation Europe PMC
4630978 PubMed citation Europe PMC
5103138 PubMed citation Europe PMC
5103535 PubMed citation Europe PMC
5168706 PubMed citation Europe PMC
6153524 PubMed citation Europe PMC
6813319 PubMed citation Europe PMC
6975776 PubMed citation Europe PMC
6992777 PubMed citation Europe PMC
701277 PubMed citation Europe PMC
7142115 PubMed citation Europe PMC
7144800 PubMed citation Europe PMC
7766032 PubMed citation Europe PMC
Last Modified
04 August 2014