CHEBI:28492 - 5-methylbarbituric acid

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name 5-methylbarbituric acid
ChEBI ID CHEBI:28492
Stars This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs CHEBI:2093, CHEBI:20606
Supplier Information
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Formula C5H6N2O3
Net Charge 0
Average Mass 142.11282
Monoisotopic Mass 142.03784
InChI InChI=1S/C5H6N2O3/c1-2-3(8)6-5(10)7-4(2)9/h2H,1H3,(H2,6,7,8,9,10)
InChIKey GOMAEJQBTWAPAN-UHFFFAOYSA-N
SMILES CC1C(=O)NC(=O)NC1=O
Roles Classification
Biological Role(s): GABA modulator
A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
(via barbiturates )
Application(s): GABA modulator
A substance that does not act as agonist or antagonist but does affect the gamma-aminobutyric acid receptor-ionophore complex. GABA-A receptors appear to have at least three allosteric sites at which modulators act: a site at which benzodiazepines act by increasing the opening frequency of gamma-aminobutyric acid-activated chloride channels; a site at which barbiturates act to prolong the duration of channel opening; and a site at which some steroids may act.
(via barbiturates )
View more via ChEBI Ontology
ChEBI Ontology
Outgoing 5-methylbarbituric acid (CHEBI:28492) is a barbiturates (CHEBI:22693)
5-methylbarbituric acid (CHEBI:28492) is conjugate acid of 5-methylbarbituride (CHEBI:58571)
Incoming 5-methylbarbituride (CHEBI:58571) is conjugate base of 5-methylbarbituric acid (CHEBI:28492)
IUPAC Name
5-methylpyrimidine-2,4,6(1H,3H,5H)-trione
Synonyms Sources
5-methyl-2,4,6(1H,3H,5H)-pyrimidinetrione ChemIDplus
5-Methylbarbiturate KEGG COMPOUND
5-Methylbarbituric acid KEGG COMPOUND
5-methylbarbituric acid ChemIDplus
Manual Xref Database
C05281 KEGG COMPOUND
View more database links
Registry Numbers Types Sources
127336 Beilstein Registry Number Beilstein
2417-22-3 CAS Registry Number KEGG COMPOUND
2417-22-3 CAS Registry Number ChemIDplus
Last Modified
28 July 2014