CHEBI:25461 - myxothiazol

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ChEBI Name myxothiazol
ChEBI ID CHEBI:25461
Definition A 2,4'-bi-1,3-thiazole substituted at the 4-position with a (1E,3S,4R,5E)-7-amino-3,5-dimethoxy-4-methyl-7-oxohepta-1,5-dien-1-yl] group and at the 2'-position with a (2S,3E,5E)-7-methylocta-3,5-dien-2-yl group. It is an inhibitor of coenzyme Q - cytochrome c reductase.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Formula C25H33N3O3S2
Net Charge 0
Average Mass 487.67800
Monoisotopic Mass 487.196
InChI InChI=1S/C25H33N3O3S2/c1-16(2)9-7-8-10-17(3)24-28-20(15-33-24)25-27-19(14-32-25)11-12-21(30-5)18(4)22(31-6)13-23(26)29/h7-18,21H,1-6H3,(H2,26,29)/b9-7+,10-8+,12-11+,22-13+/t17?,18-,21+/m1/s1
InChIKey XKTFQMCPGMTBMD-YCSHSZEBSA-N
SMILES CO[C@@H](\C=C\c1csc(n1)-c1csc(n1)C(C)\C=C\C=C\C(C)C)[C@@H](C)C(\OC)=C/C(N)=O
Roles Classification
Biological Role(s): metabolite
Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
mitochondrial respiratory-chain inhibitor

View more via ChEBI Ontology
ChEBI Ontology
Outgoing myxothiazol (CHEBI:25461) has role metabolite (CHEBI:25212)
myxothiazol (CHEBI:25461) has role mitochondrial respiratory-chain inhibitor (CHEBI:25355)
myxothiazol (CHEBI:25461) is a 1,3-thiazoles (CHEBI:38418)
myxothiazol (CHEBI:25461) is a monocarboxylic acid amide (CHEBI:29347)
IUPAC Name
(2E,4R,5S,6E)-3,5-dimethoxy-4-methyl-7-{2'-[(2S,3E,5E)-7-methylocta-3,5-dien-2-yl]-2,4'-bi-1,3-thiazol-4-yl}hepta-2,6-dienamide
Synonyms Sources
(+)-myxothiazol ChEBI
Myxothiazol A KEGG COMPOUND
Manual Xrefs Databases
C00018319 KNApSAcK
C15674 KEGG COMPOUND
DB04741 DrugBank
MYX PDBeChem
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Registry Number Type Source
76706-55-3 CAS Registry Number ChemIDplus
Last Modified
26 October 2017