CHEBI:23995 - N-ethyl-N-nitrosourea

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ChEBI Name N-ethyl-N-nitrosourea
ChEBI ASCII Name N-ethyl-N-nitrosourea
Definition A member of the class of N-nitrosoureas that is urea in which one of the nitrogens is substituted by ethyl and nitroso groups.
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C3H7N3O2
Net Charge 0
Average Mass 117.10660
Monoisotopic Mass 117.05383
InChI InChI=1S/C3H7N3O2/c1-2-6(5-8)3(4)7/h2H2,1H3,(H2,4,7)
Roles Classification
Biological Role(s): mutagen
An agent that increases the frequency of mutations above the normal background level, usually by interacting directly with DNA and causing it damage, including base substitution.
carcinogenic agent
A role played by a chemical compound which is known to induce a process of carcinogenesis by corrupting normal cellular pathways, leading to the acquistion of tumoral capabilities.
A role played by a chemical compound to induce direct or indirect DNA damage. Such damage can potentially lead to the formation of a malignant tumour, but DNA damage does not lead inevitably to the creation of cancerous cells.
alkylating agent
Highly reactive chemical that introduces alkyl radicals into biologically active molecules and thereby prevents their proper functioning. It could be used as an antineoplastic agent, but it might be very toxic, with carcinogenic, mutagenic, teratogenic, and immunosuppressant actions. It could also be used as a component of poison gases.
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ChEBI Ontology
Outgoing N-ethyl-N-nitrosourea (CHEBI:23995) has functional parent urea (CHEBI:16199)
N-ethyl-N-nitrosourea (CHEBI:23995) has role alkylating agent (CHEBI:22333)
N-ethyl-N-nitrosourea (CHEBI:23995) has role carcinogenic agent (CHEBI:50903)
N-ethyl-N-nitrosourea (CHEBI:23995) has role genotoxin (CHEBI:50902)
N-ethyl-N-nitrosourea (CHEBI:23995) has role mutagen (CHEBI:25435)
N-ethyl-N-nitrosourea (CHEBI:23995) is a N-nitrosoureas (CHEBI:76551)
Synonyms Sources
1-(Aminocarbonyl)-1-ethyl-2-oxohydrazine NIST Chemistry WebBook
1-Ethyl-1-nitrosourea ChemIDplus
Aethylnitroso-harnstoff ChemIDplus
ENU ChemIDplus
Ethyl nitrosourea ChemIDplus
N-Ethyl-N-nitroso carbamide ChemIDplus
N-Ethyl-N-nitroso-urea ChemIDplus
N-Ethylnitrosourea ChemIDplus
NEU NIST Chemistry WebBook
Manual Xrefs Databases
ENU Wikipedia
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Registry Numbers Types Sources
1761174 Reaxys Registry Number Reaxys
1761174 Beilstein Registry Number Beilstein
759-73-9 CAS Registry Number ChemIDplus
759-73-9 CAS Registry Number NIST Chemistry WebBook
Citations Waiting for Citations Types Sources
11732210 PubMed citation Europe PMC
11853764 PubMed citation Europe PMC
11880538 PubMed citation Europe PMC
16423555 PubMed citation Europe PMC
21861612 PubMed citation Europe PMC
22012195 PubMed citation Europe PMC
22238669 PubMed citation Europe PMC
23551873 PubMed citation Europe PMC
24175309 PubMed citation Europe PMC
8603364 PubMed citation Europe PMC
Last Modified
28 July 2014