CHEBI:23899 - icosanoid

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ChEBI Name icosanoid
ChEBI ID CHEBI:23899
Definition Any member of the group of signalling molecules arising from oxidation of the three C20 essential fatty acids (EFAs) icosapentaenoic acid (EPA), arachidonic acid (AA) and dihomo-gamma-linolenic acid (DGLA).
Stars This entity has been manually annotated by the ChEBI Team.
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ChEBI Ontology
Outgoing icosanoid (CHEBI:23899) is a fatty acid derivative (CHEBI:61697)
icosanoid (CHEBI:23899) is conjugate acid of icosanoid anion (CHEBI:62937)
Incoming (5Z,9E,12S,14Z)-8,11,12,20-tetrahydroxyicosa-5,9,14-trienoic acid (CHEBI:83782) is a icosanoid (CHEBI:23899)
(6E,8Z,10E,12S,14Z)-12-hydroxy-5-oxoicosatetraenoic acid (CHEBI:137749) is a icosanoid (CHEBI:23899)
(6E,8Z,11Z,13E,15S)-15-hydroxy-5-oxoicosatetraenoic acid (CHEBI:137746) is a icosanoid (CHEBI:23899)
(6E,8Z,11Z,14Z,17Z)-5-oxoicosapentaenoic acid (CHEBI:140244) is a icosanoid (CHEBI:23899)
(7R)-hydroxy-(5S,6S)-epoxy-(8Z,11Z,14Z)-icosatrienoic acid (CHEBI:75825) is a icosanoid (CHEBI:23899)
12(S)-HPE(5,8,10)TrE (CHEBI:78859) is a icosanoid (CHEBI:23899)
12-HPE(8,10,14)TrE (CHEBI:84174) is a icosanoid (CHEBI:23899)
13,14-dihydro-15-oxolipoxin A4 (CHEBI:63993) is a icosanoid (CHEBI:23899)
13,14-dihydrolipoxin A4 (CHEBI:79199) is a icosanoid (CHEBI:23899)
14-carboxy-15,16,17,18,19,20-hexanor-leukotriene E3 (CHEBI:74019) is a icosanoid (CHEBI:23899)
16-carboxy-Δ13-17,18,19,20-tetranor-leukotriene E4 (CHEBI:74016) is a icosanoid (CHEBI:23899)
16-carboxy-17,18,19,20-tetranor-leukotriene E3 (CHEBI:74014) is a icosanoid (CHEBI:23899)
18-carboxy-19,20-dinor-leukotriene E4 (CHEBI:74017) is a icosanoid (CHEBI:23899)
5(S),6(S)-epoxy-18(R)-hydroxy-(7E,9E,11Z,14Z,16E)-icosapentaenoic acid (CHEBI:132909) is a icosanoid (CHEBI:23899)
5(S),6(S)-epoxy-18-hydroxy-(7E,9E,11Z,14Z,16E)-icosapentaenoic acid (CHEBI:136355) is a icosanoid (CHEBI:23899)
5,20-diHEPE (CHEBI:130073) is a icosanoid (CHEBI:23899)
5,8,11-icosatriynoic acid (CHEBI:53454) is a icosanoid (CHEBI:23899)
5-hydroperoxy-15-HETE (CHEBI:90833) is a icosanoid (CHEBI:23899)
bis(hydroperoxy)icosatetraenoic acid (CHEBI:138293) is a icosanoid (CHEBI:23899)
DG(14:0/20:2(11Z,14Z)/0:0) (CHEBI:88796) is a icosanoid (CHEBI:23899)
DG(14:0/20:3(5Z,8Z,11Z)/0:0) (CHEBI:88794) is a icosanoid (CHEBI:23899)
DG(14:0/20:3(8Z,11Z,14Z)/0:0) (CHEBI:88805) is a icosanoid (CHEBI:23899)
DG(14:0/20:4(5Z,8Z,11Z,14Z)/0:0) (CHEBI:88804) is a icosanoid (CHEBI:23899)
DG(14:0/20:4(8Z,11Z,14Z,17Z)/0:0) (CHEBI:88803) is a icosanoid (CHEBI:23899)
DG(14:1(9Z)/20:2(11Z,14Z)/0:0) (CHEBI:88723) is a icosanoid (CHEBI:23899)
DG(14:1(9Z)/20:3(5Z,8Z,11Z)/0:0) (CHEBI:88724) is a icosanoid (CHEBI:23899)
DG(14:1(9Z)/20:3(8Z,11Z,14Z)/0:0) (CHEBI:88722) is a icosanoid (CHEBI:23899)
DHET (CHEBI:64005) is a icosanoid (CHEBI:23899)
dihydroxyicosatetraenoic acid (CHEBI:72868) is a icosanoid (CHEBI:23899)
EET (CHEBI:64007) is a icosanoid (CHEBI:23899)
EpETE (CHEBI:72852) is a icosanoid (CHEBI:23899)
HETE (CHEBI:36275) is a icosanoid (CHEBI:23899)
HPETE (CHEBI:24644) is a icosanoid (CHEBI:23899)
hydroperoxy(epoxy)icosatrienoic acid (CHEBI:134641) is a icosanoid (CHEBI:23899)
hydroperoxy(hydroxy)icosapentaenoic acid (CHEBI:134645) is a icosanoid (CHEBI:23899)
hydroperoxy(hydroxy)icosatetraenoic acid (CHEBI:138327) is a icosanoid (CHEBI:23899)
hydroperoxyicosapentaenoic acid (CHEBI:138392) is a icosanoid (CHEBI:23899)
hydroperoxyicosatrienoic acid (CHEBI:136627) is a icosanoid (CHEBI:23899)
icosenoic acid (CHEBI:23902) is a icosanoid (CHEBI:23899)
isoprostane (CHEBI:138408) is a icosanoid (CHEBI:23899)
leukotriene (CHEBI:25029) is a icosanoid (CHEBI:23899)
levuglandin (CHEBI:36142) is a icosanoid (CHEBI:23899)
nonclassic icosanoid (CHEBI:61703) is a icosanoid (CHEBI:23899)
prostanoid (CHEBI:26347) is a icosanoid (CHEBI:23899)
icosanoid anion (CHEBI:62937) is conjugate base of icosanoid (CHEBI:23899)
Synonyms Sources
eicosanoid ChEBI
eicosanoids ChEBI
icosanoid LIPID MAPS
icosanoids ChEBI
Manual Xrefs Databases
Eicosanoid Wikipedia
LMFA03 LIPID MAPS
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Citations Waiting for Citations Types Sources
12697726 PubMed citation Europe PMC
16107763 PubMed citation Europe PMC
19160658 PubMed citation Europe PMC
2657063 PubMed citation Europe PMC
Last Modified
05 March 2018
General Comments
2011-03-23 A particular eicosanoid is denoted by a four-character abbreviation, composed of: (i)its two-letter abbreviation; (ii) one A-B-C sequence letter; and (iii) a subscript, indicating the number of double bonds.
2011-03-23 Functioning as autocrine hormones, they exert complex control over a wide diversity of physiological processes, mainly in inflammation or immunity.
2011-03-24 Current usage limits the term to the leukotrienes (LT) and the prostanoids (prostaglandins (PG), prostacyclins (PGI) and thromboxanes (TX)).