CHEBI:222828 - monoethylglycinexylidide

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ChEBI Name monoethylglycinexylidide
ChEBI ID CHEBI:222828
Definition Amino acid amide formed from 2,6-dimethylaniline and N-ethylglycine components; an active metabolite of lidocaine, formed by oxidative deethylation. Used as an indicator of hepatic function.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Formula C12H18N2O
Net Charge 0
Average Mass 206.28410
Monoisotopic Mass 206.14191
InChI InChI=1S/C12H18N2O/c1-4-13-8-11(15)14-12-9(2)6-5-7-10(12)3/h5-7,13H,4,8H2,1-3H3,(H,14,15)
InChIKey WRMRXPASUROZGT-UHFFFAOYSA-N
SMILES CCNCC(=O)Nc1c(C)cccc1C
Roles Classification
Biological Role(s): drug metabolite

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ChEBI Ontology
Outgoing monoethylglycinexylidide (CHEBI:222828) has role drug metabolite (CHEBI:49103)
monoethylglycinexylidide (CHEBI:222828) is a amino acid amide (CHEBI:22475)
Incoming monoethylglycinexylidide hydrochloride (CHEBI:55524) has part monoethylglycinexylidide (CHEBI:222828)
IUPAC Name
N-(2,6-dimethylphenyl)-N2-ethylglycinamide
Synonyms Sources
2-Ethylamino-2',6'-acetoxylidide ChemIDplus
2-Ethylamino-2,6-acetoxylidine ChemIDplus
Ethylglycylxylidide ChemIDplus
Lidocaine N-de-ethylated metabolite NIST Chemistry WebBook
N-(2,6-Dimethylphenyl)-2-(ethylamino)acetamide ChemIDplus
N-Ethylglycinexylidide ChemIDplus
norlidocaine ChEBI
ω-(ethylamino)-2',6'-dimethylacetanilide NIST Chemistry WebBook
Manual Xrefs Databases
C16561 KEGG COMPOUND
HMDB0060656 HMDB
View more database links
Registry Numbers Types Sources
2417108 Beilstein Registry Number Beilstein
2417108 Reaxys Registry Number Reaxys
7728-40-7 CAS Registry Number ChemIDplus
7728-40-7 CAS Registry Number NIST Chemistry WebBook
Citations Waiting for Citations Types Sources
17296334 PubMed citation Europe PMC
22212047 PubMed citation Europe PMC
22452841 PubMed citation Europe PMC
22468031 PubMed citation Europe PMC
7071904 PubMed citation Europe PMC
9989796 PubMed citation Europe PMC
Last Modified
20 January 2015