CHEBI:16810 - 2-oxoglutarate(2−)

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ChEBI Name 2-oxoglutarate(2−)
ChEBI ASCII Name 2-oxoglutarate(2-)
Definition An oxo dicarboxylate obtained by deprotonation of both carboxy groups of 2-oxoglutaric acid.
Stars This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs CHEBI:11638, CHEBI:19748
Supplier Information
Download Molfile XML SDF
Formula C5H4O5
Net Charge -2
Average Mass 144.08226
Monoisotopic Mass 144.00697
InChI InChI=1S/C5H6O5/c6-3(5(9)10)1-2-4(7)8/h1-2H2,(H,7,8)(H,9,10)/p-2
SMILES [O-]C(=O)CCC(=O)C([O-])=O
Metabolite of Species Details
Chlamydomonas reinhardtii (NCBI:txid3055) See: PubMed
Saccharomyces cerevisiae (NCBI:txid4932) Source: See: PubMed
Homo sapiens (NCBI:txid9606) See: DOI
Roles Classification
Biological Role(s): Saccharomyces cerevisiae metabolite
Any fungal metabolite produced during a metabolic reaction in Baker's yeast (Saccharomyces cerevisiae ).
human metabolite
Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens).
algal metabolite
Any eukaryotic metabolite produced during a metabolic reaction in algae including unicellular organisms like chlorella and diatoms to multicellular organisms like giant kelps and brown algae.
Application(s): geroprotector
Any compound that supports healthy aging, slows the biological aging process, or extends lifespan.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing 2-oxoglutarate(2−) (CHEBI:16810) has functional parent glutarate(2−) (CHEBI:30921)
2-oxoglutarate(2−) (CHEBI:16810) has role Saccharomyces cerevisiae metabolite (CHEBI:75772)
2-oxoglutarate(2−) (CHEBI:16810) has role algal metabolite (CHEBI:84735)
2-oxoglutarate(2−) (CHEBI:16810) has role geroprotector (CHEBI:176497)
2-oxoglutarate(2−) (CHEBI:16810) has role human metabolite (CHEBI:77746)
2-oxoglutarate(2−) (CHEBI:16810) is a oxo dicarboxylate (CHEBI:36147)
2-oxoglutarate(2−) (CHEBI:16810) is conjugate base of 2-oxoglutarate(1−) (CHEBI:30916)
Incoming 2-oxoglutarate(1−) (CHEBI:30916) is conjugate acid of 2-oxoglutarate(2−) (CHEBI:16810)
Synonyms Sources
2-ketoglutarate ChEBI
2-oxoglutarate UniProt
2-oxopentanedioic acid, ion(2−) ChemIDplus
α-ketoglutarate ChEBI
Manual Xrefs Databases
View more database links
Registry Numbers Types Sources
3664503 Beilstein Registry Number Beilstein
3664503 Reaxys Registry Number Reaxys
602479 Gmelin Registry Number Gmelin
64-15-3 CAS Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
11913971 PubMed citation Europe PMC
15612731 PubMed citation Europe PMC
17190852 PubMed citation Europe PMC
19376872 PubMed citation Europe PMC
21184277 PubMed citation Europe PMC
21196226 PubMed citation Europe PMC
21791173 PubMed citation Europe PMC
24828042 PubMed citation Europe PMC
Last Modified
28 October 2021