CHEBI:18376 - dermatan sulfate

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ChEBI Name dermatan sulfate
Definition Any of a group of glycosaminoglycans with repeating units consisting of variously sulfated β1→4-linked L-iduronyl-(α1→3)-N-acetyl-D-galactosamine units.
Stars This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs CHEBI:4440, CHEBI:14127, CHEBI:23644
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Formula H2O.(C14H20NO13S)n
Roles Classification
Application(s): hematologic agent
Drug that acts on blood and blood-forming organs and those that affect the hemostatic system.
An agent that prevents blood clotting.
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ChEBI Ontology
Outgoing dermatan sulfate (CHEBI:18376) has functional parent dermatan (CHEBI:4439)
dermatan sulfate (CHEBI:18376) has role anticoagulant (CHEBI:50249)
dermatan sulfate (CHEBI:18376) has role hematologic agent (CHEBI:50248)
dermatan sulfate (CHEBI:18376) is a mucopolysaccharide (CHEBI:37395)
dermatan sulfate (CHEBI:18376) is a sulfated glycosaminoglycan (CHEBI:35722)
dermatan sulfate (CHEBI:18376) is conjugate acid of dermatan sulfate polyanion (CHEBI:58465)
Incoming dermatan sulfate polyanion (CHEBI:58465) is conjugate base of dermatan sulfate (CHEBI:18376)
Synonyms Sources
beta-Heparin KEGG COMPOUND
Chondroitin sulfate B KEGG COMPOUND
Dermatan L-iduronate KEGG COMPOUND
Manual Xref Database
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Registry Numbers Types Sources
24967-94-0 CAS Registry Number KEGG COMPOUND
24967-94-0 CAS Registry Number ChemIDplus
8390617 Beilstein Registry Number Beilstein
Last Modified
17 February 2017
General Comment
2009-07-23 The structure shown is an example of a repeating unit. Each monosaccharide may be unsulfated, sulfated once, or sulfated twice. Most commonly the hydroxy groups of the 4- and 6-positions of the N-acetyl-galactosamine are sulfated, with some chains also having sulfation at the 2-position of the iduronic acid.