CHEBI:177836 - (E)-dacarbazine

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ChEBI Name (E)-dacarbazine
ChEBI ASCII Name (E)-dacarbazine
Definition A dacarbazine in which the N=N double bond adopts a trans-configuration.
Stars This entity has been manually annotated by the ChEBI Team.
Submitter MetaboLights
Supplier Information
Download Molfile XML SDF
Formula C6H10N6O
Net Charge 0
Average Mass 182.187
Monoisotopic Mass 182.09161
InChI InChI=1S/C6H10N6O/c1-12(2)11-10-6-4(5(7)13)8-3-9-6/h3H,1-2H3,(H2,7,13)(H,8,9)/b11-10+
Metabolite of Species Details
Sus scrofa (NCBI:txid9823) Found in sausage (ENVO:00002166). See: MetaboLights Study
Roles Classification
Biological Role(s): alkylating agent
Highly reactive chemical that introduces alkyl radicals into biologically active molecules and thereby prevents their proper functioning. It could be used as an antineoplastic agent, but it might be very toxic, with carcinogenic, mutagenic, teratogenic, and immunosuppressant actions. It could also be used as a component of poison gases.
(via dacarbazine )
carcinogenic agent
A role played by a chemical compound which is known to induce a process of carcinogenesis by corrupting normal cellular pathways, leading to the acquistion of tumoral capabilities.
(via dacarbazine )
Application(s): antineoplastic agent
A substance that inhibits or prevents the proliferation of neoplasms.
(via dacarbazine )
A compound that, on administration, must undergo chemical conversion by metabolic processes before becoming the pharmacologically active drug for which it is a prodrug.
(via dacarbazine )
View more via ChEBI Ontology
ChEBI Ontology
Outgoing (E)-dacarbazine (CHEBI:177836) is a dacarbazine (CHEBI:4305)
Synonym Source
trans-dacarbazine ChEBI
Manual Xref Database
10481959 ChemSpider
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Last Modified
04 November 2021