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CHEBI:17158 - methylglyoxal

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name methylglyoxal
Definition A 2-oxo aldehyde derived from propanal.
Stars This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs CHEBI:6875, CHEBI:11643, CHEBI:14599, CHEBI:25303
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Formula C3H4O2
Net Charge 0
Average Mass 72.06266
Monoisotopic Mass 72.021
InChI InChI=1S/C3H4O2/c1-3(5)2-4/h2H,1H3
Metabolite of Species Details
Mus musculus (NCBI:10090) Source: BioModels - MODEL1507180067 See: PubMed
Saccharomyces cerevisiae (NCBI:4932) Source: See: PubMed
Escherichia coli (NCBI:562) See: PubMed
Homo sapiens (NCBI:9606) See: DOI
Roles Classification
Biological Role(s): Escherichia coli metabolite
Any bacterial metabolite produced during a metabolic reaction in Escherichia coli.
Saccharomyces cerevisiae metabolite
Any fungal metabolite produced during a metabolic reaction in Baker's yeast (Saccharomyces cerevisiae ).
human metabolite
Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens).
mouse metabolite
Any mammalian metabolite produced during a metabolic reaction in a mouse (Mus musculus).
View more via ChEBI Ontology
ChEBI Ontology
Outgoing methylglyoxal (CHEBI:17158) has role Escherichia coli metabolite (CHEBI:76971)
methylglyoxal (CHEBI:17158) has role Saccharomyces cerevisiae metabolite (CHEBI:75772)
methylglyoxal (CHEBI:17158) has role human metabolite (CHEBI:77746)
methylglyoxal (CHEBI:17158) has role mouse metabolite (CHEBI:75771)
methylglyoxal (CHEBI:17158) is a 2-oxo aldehyde (CHEBI:27659)
methylglyoxal (CHEBI:17158) is a propanals (CHEBI:26282)
Incoming mitoguazone (CHEBI:43996) has functional parent methylglyoxal (CHEBI:17158)
Synonyms Sources
1,2-propanedione NIST Chemistry WebBook
2-Ketopropionaldehyde KEGG COMPOUND
2-Oxopropanal KEGG COMPOUND
2-oxopropanal UniProt
2-oxopropionaldehyde ChemIDplus
acetylformaldehyde ChemIDplus
acetylformyl NIST Chemistry WebBook
α-ketopropionaldehyde NIST Chemistry WebBook
CH3COCHO NIST Chemistry WebBook
Methylglyoxal KEGG COMPOUND
Pyruvaldehyde KEGG COMPOUND
Pyruvic aldehyde KEGG COMPOUND
Database Links Databases
C00007562 KNApSAcK
Methylglyoxal Wikipedia
View more database links
Registry Numbers Types Sources
78-98-8 CAS Registry Number ChemIDplus
78-98-8 CAS Registry Number NIST Chemistry WebBook
906750 Beilstein Registry Number Beilstein
906750 Reaxys Registry Number Reaxys
Citations Waiting for Citations Types Sources
10373458 PubMed citation Europe PMC
10723098 PubMed citation Europe PMC
11504881 PubMed citation Europe PMC
15520007 PubMed citation Europe PMC
17103372 PubMed citation Europe PMC
19202315 PubMed citation Europe PMC
20096340 PubMed citation Europe PMC
22983866 PubMed citation Europe PMC
23543734 PubMed citation Europe PMC
23845007 PubMed citation Europe PMC
24040205 PubMed citation Europe PMC
24168114 PubMed citation Europe PMC
26861824 PubMed citation Europe PMC
9506998 PubMed citation Europe PMC
Last Modified
05 July 2016
General Comment
2011-01-26 Formed endogenously in numerous reactions, it modifies Arg and Lys residues in proteins, forming advanced glycation end-products which are associated with complications of diabetes and some neurodegenerative diseases.