CHEBI:166776 - 20α-dihydroprednisolone

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name 20α-dihydroprednisolone
ChEBI ID CHEBI:166776
ChEBI ASCII Name 20alpha-dihydroprednisolone
Definition A glucocorticoid that is prednisolone in which the oxo group at position 20 has been reduced to the corresponding α-hydroxy group. It is a metabolite of prednisolone.
Stars This entity has been manually annotated by the ChEBI Team.
Submitter MetaboLights
Supplier Information
Download Molfile XML SDF
Formula C21H30O5
Net Charge 0
Average Mass 362.466
Monoisotopic Mass 362.20932
InChI InChI=1S/C21H30O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h5,7,9,14-18,22,24-26H,3-4,6,8,10-11H2,1-2H3/t14-,15-,16-,17+,18+,19-,20-,21-/m0/s1
InChIKey LCOVYWIXMAJCDS-LCGKLAOVSA-N
SMILES [H][C@@]12CC[C@](O)([C@H](O)CO)[C@@]1(C)C[C@H](O)[C@@]1([H])[C@@]2([H])CCC2=CC(=O)C=C[C@]12C
Roles Classification
Biological Role(s): hormone
Originally referring to an endogenous compound that is formed in specialized organ or group of cells and carried to another organ or group of cells, in the same organism, upon which it has a specific regulatory function, the term is now commonly used to include non-endogenous, semi-synthetic and fully synthetic analogues of such compounds.
(via steroid hormone )
View more via ChEBI Ontology
ChEBI Ontology
Outgoing 20α-dihydroprednisolone (CHEBI:166776) has functional parent prednisolone (CHEBI:8378)
20α-dihydroprednisolone (CHEBI:166776) is a 11β-hydroxy steroid (CHEBI:35346)
20α-dihydroprednisolone (CHEBI:166776) is a 17α-hydroxy steroid (CHEBI:35342)
20α-dihydroprednisolone (CHEBI:166776) is a 20-hydroxy steroid (CHEBI:36854)
20α-dihydroprednisolone (CHEBI:166776) is a 21-hydroxy steroid (CHEBI:35344)
20α-dihydroprednisolone (CHEBI:166776) is a 3-oxo-Δ1,Δ4-steroid (CHEBI:77166)
20α-dihydroprednisolone (CHEBI:166776) is a C21-steroid (CHEBI:61313)
20α-dihydroprednisolone (CHEBI:166776) is a glucocorticoid (CHEBI:24261)
IUPAC Name
(20R)-11β,17,20,21-tetrahydroxypregna-1,4-dien-3-one
Synonyms Sources
(11β,20R)-11,17,20,21-tetrahydroxypregna-1,4-dien-3-one ChEBI
(20R)-hydroxyprednisolone ChEBI
20(R)-hydroxy prednisolone ChEBI
20α-dihydro-PRED ChEBI
20α-dihydro-prednisolone ChEBI
20α-hydroxy prednisolone ChEBI
20α-hydroxyprednisolone ChEBI
Manual Xref Database
27524367 ChemSpider
View more database links
Registry Number Type Source
15847-24-2 CAS Registry Number ChEBI
Citations Waiting for Citations Types Sources
2055997 PubMed citation Europe PMC
23510304 PubMed citation Europe PMC
28806969 PubMed citation Europe PMC
34081842 PubMed citation Europe PMC
Last Modified
27 January 2022