CHEBI:16628 - methylguanidine

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ChEBI Name methylguanidine
ChEBI ID CHEBI:16628
Definition A guanidine in which one of the amino hydrogens of guanidine itself is substituted by a methyl group.
Stars This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs CHEBI:43998, CHEBI:6876, CHEBI:14600, CHEBI:25304
Supplier Information
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Formula C2H7N3
Net Charge 0
Average Mass 73.09720
Monoisotopic Mass 73.06400
InChI InChI=1S/C2H7N3/c1-5-2(3)4/h1H3,(H4,3,4,5)
InChIKey CHJJGSNFBQVOTG-UHFFFAOYSA-N
SMILES CNC(N)=N
Roles Classification
Biological Role(s): EC 1.14.13.39 (nitric oxide synthase) inhibitor
An EC 1.14.13.* (oxidoreductase acting on paired donors, incorporating 1 atom of oxygen, with NADH or NADPH as one donor) inhibitor that interferes with the action of nitric oxide synthase (EC 1.14.13.39).
uremic toxin
A toxin that accumulates in patients with chronic kidney disease.
metabolite
Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing methylguanidine (CHEBI:16628) has role EC 1.14.13.39 (nitric oxide synthase) inhibitor (CHEBI:61908)
methylguanidine (CHEBI:16628) has role metabolite (CHEBI:25212)
methylguanidine (CHEBI:16628) has role uremic toxin (CHEBI:64584)
methylguanidine (CHEBI:16628) is a guanidines (CHEBI:24436)
methylguanidine (CHEBI:16628) is conjugate base of methylguanidinium (CHEBI:57840)
Incoming Glu-Trp-Asp-Arg (CHEBI:138509) has functional parent methylguanidine (CHEBI:16628)
methylguanidinium (CHEBI:57840) is conjugate acid of methylguanidine (CHEBI:16628)
IUPAC Name
1-methylguanidine
Synonyms Sources
1-METHYLGUANIDINE PDBeChem
Methylguanidin ChemIDplus
Methylguanidine KEGG COMPOUND
MGX HMDB
Monomethyl guanidin HMDB
monomethylguanidine NIST Chemistry WebBook
N-methylguanidine NIST Chemistry WebBook
N1-Methylguanidine HMDB
Manual Xrefs Databases
C02294 KEGG COMPOUND
CPD-593 MetaCyc
HMDB0001522 HMDB
MGX PDBeChem
PL391702 Patent
View more database links
Registry Numbers Types Sources
1738993 Reaxys Registry Number Reaxys
1738993 Beilstein Registry Number Beilstein
323399 Gmelin Registry Number Gmelin
471-29-4 CAS Registry Number ChemIDplus
471-29-4 CAS Registry Number NIST Chemistry WebBook
Citations Waiting for Citations Types Sources
14744621 PubMed citation Europe PMC
17190852 PubMed citation Europe PMC
17409514 PubMed citation Europe PMC
19286340 PubMed citation Europe PMC
21090628 PubMed citation Europe PMC
22342614 PubMed citation Europe PMC
Last Modified
25 September 2017