CHEBI:16480 - nitric oxide

Main ChEBI Ontology Automatic Xrefs
ChEBI Name nitric oxide
ChEBI ID CHEBI:16480
Definition A nitrogen oxide which is a free radical, each molecule of which consists of one nitrogen and one oxygen atom.
Stars This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs CHEBI:14657, CHEBI:44452, CHEBI:25546, CHEBI:7583
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Formula NO
Net Charge 0
Average Mass 30.00614
InChI InChI=1S/NO/c1-2
InChIKey MWUXSHHQAYIFBG-UHFFFAOYSA-N
SMILES [N]=O
Metabolite of Species Details
Homo sapiens (NCBI:9606) See: DOI
Roles Classification
Chemical Role(s): radical scavenger
A role played by a substance that can react readily with, and thereby eliminate, radicals.
Biological Role(s): human metabolite
Any mammalian metabolite produced during a metabolic reaction in humans (Homo sapiens).
neurotransmitter
An endogenous compound that is used to transmit information across the synapse between a neuron and another cell.
signalling molecule
A molecular messenger in which the molecule is specifically involved in transmitting information between cells. Such molecules are released from the cell sending the signal, cross over the gap between cells by diffusion, and interact with specific receptors in another cell, triggering a response in that cell by activating a series of enzyme controlled reactions which lead to changes inside the cell.
Application(s): bronchodilator agent
An agent that causes an increase in the expansion of a bronchus or bronchial tubes.
vasodilator agent
A drug used to cause dilation of the blood vessels.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing nitric oxide (CHEBI:16480) has role bronchodilator agent (CHEBI:35523)
nitric oxide (CHEBI:16480) has role human metabolite (CHEBI:77746)
nitric oxide (CHEBI:16480) has role neurotransmitter (CHEBI:25512)
nitric oxide (CHEBI:16480) has role radical scavenger (CHEBI:48578)
nitric oxide (CHEBI:16480) has role signalling molecule (CHEBI:62488)
nitric oxide (CHEBI:16480) has role vasodilator agent (CHEBI:35620)
nitric oxide (CHEBI:16480) is a inorganic radical (CHEBI:36871)
nitric oxide (CHEBI:16480) is a nitrogen oxide (CHEBI:35196)
nitric oxide (CHEBI:16480) is a reactive nitrogen species (CHEBI:62764)
nitric oxide (CHEBI:16480) is a reactive oxygen species (CHEBI:26523)
IUPAC Names
oxidonitrogen(•)
oxoazanyl
Synonyms Sources
(NO) IUPAC
[NO] MolBase
EDRF ChEBI
endothelium-derived relaxing factor ChEBI
mononitrogen monoxide ChemIDplus
monóxido de nitrógeno ChEBI
monoxyde d'azote ChEBI
Nitric oxide KEGG COMPOUND
nitric oxide UniProt
nitrogen monooxide IUPAC
Nitrogen monoxide KEGG COMPOUND
nitrogen monoxide IUPAC
nitrosyl IUPAC
NO KEGG COMPOUND
NO ChEBI
NO IUPAC
óxido de nitrógeno(II) ChEBI
óxido nítrico ChEBI
oxyde azotique ChEBI
oxyde nitrique ChEBI
Stickstoff(II)-oxid ChEBI
Stickstoffmonoxid ChEBI
Database Links Databases
943 MolBase
C00533 KEGG COMPOUND
D00074 KEGG DRUG
DB00435 DrugBank
Nitric oxide Wikipedia
NO PDBeChem
View more database links
Registry Numbers Types Sources
10102-43-9 CAS Registry Number KEGG COMPOUND
10102-43-9 CAS Registry Number ChemIDplus
10102-43-9 CAS Registry Number NIST Chemistry WebBook
3587257 Reaxys Registry Number Reaxys
451 Gmelin Registry Number Gmelin
Last Modified
04 August 2014
General Comment
2012-07-23 Nitric oxide (NO) is a relatively stable free radical. A significant air pollutant, being produced by combustion of substances in air, particularly of fossil fuels in power stations and internal combustion engines, it is also an important signalling molecule, involved in many physiological and pathological processes in mammals.