CHEBI:15738 - staurosporine

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name staurosporine
ChEBI ID CHEBI:15738
Stars This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs CHEBI:15106, CHEBI:45788, CHEBI:9252
Supplier Information
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Formula C28H26N4O3
Net Charge 0
Average Mass 466.53120
Monoisotopic Mass 466.200
InChI InChI=1S/C28H26N4O3/c1-28-26(34-3)17(29-2)12-20(35-28)31-18-10-6-4-8-14(18)22-23-16(13-30-27(23)33)21-15-9-5-7-11-19(15)32(28)25(21)24(22)31/h4-11,17,20,26,29H,12-13H2,1-3H3,(H,30,33)/t17-,20-,26-,28+/m1/s1
InChIKey HKSZLNNOFSGOKW-FYTWVXJKSA-N
SMILES CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4CNC(=O)c4c4c5ccccc5n2c4c13
Roles Classification
Biological Role(s): EC 2.7.11.13 (protein kinase C) inhibitor
An EC 2.7.11.* (protein-serine/threonine kinase) inhibitor that interferes with the action of protein kinase C (EC 2.7.11.13).
metabolite
Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
(via alkaloid )
View more via ChEBI Ontology
ChEBI Ontology
Outgoing staurosporine (CHEBI:15738) has role EC 2.7.11.13 (protein kinase C) inhibitor (CHEBI:37700)
staurosporine (CHEBI:15738) is a indolocarbazole alkaloid (CHEBI:37697)
staurosporine (CHEBI:15738) is a organic heterooctacyclic compound (CHEBI:38165)
staurosporine (CHEBI:15738) is conjugate base of staurosporinium (CHEBI:57491)
Incoming 3'-demethylstaurosporine (CHEBI:15692) has functional parent staurosporine (CHEBI:15738)
7-oxo-3,8,9-trihydroxy staurosporine (CHEBI:66839) has functional parent staurosporine (CHEBI:15738)
7-oxo-8,9-dihydroxy-4'-N-demethyl staurosporine (CHEBI:66840) has functional parent staurosporine (CHEBI:15738)
linkable staurosporine analogue (CHEBI:39082) has functional parent staurosporine (CHEBI:15738)
midostaurin (CHEBI:63452) has functional parent staurosporine (CHEBI:15738)
staurosporinium (CHEBI:57491) is conjugate acid of staurosporine (CHEBI:15738)
IUPAC Name
(5S,6R,7R,9R)-6-methoxy-5-methyl-7-methylamino-6,7,8,9,15,16-hexahydro-5H,14H-5,9-epoxy-4b,9a,15-triazadibenzo[b,h]cyclonona[1,2,3,4-jkl]cyclopenta[e]-as-indacen-14-one
Synonyms Sources
(+)-Staurosporine ChemIDplus
Staurosporin ChemIDplus
Staurosporine KEGG COMPOUND
STS KEGG COMPOUND
Database Links Databases
C00018127 KNApSAcK
C02079 KEGG COMPOUND
DB02010 DrugBank
LSM-1103 LINCS
View more database links
Registry Numbers Types Sources
62996-74-1 CAS Registry Number KEGG COMPOUND
62996-74-1 CAS Registry Number ChemIDplus
Last Modified
24 February 2016