CHEBI:141644 - trisodium phosphonoformate

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ChEBI Name trisodium phosphonoformate
Definition The trisodium salt of phosphonoformic acid. It is used as an antiviral agent in the treatment of cytomegalovirus retinitis (CMV retinitis, an inflamation of the retina that can lead to blindness) and as an alternative to ganciclovir for AIDS patients who require concurrent antiretroviral therapy but are unable to tolerate ganciclovir due to haematological toxicity.
Stars This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs CHEBI:5161
Supplier Information
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Formula CNa3O5P
Net Charge 0
Average Mass 191.95080
Monoisotopic Mass 191.91764
InChI InChI=1S/CH3O5P.3Na/c2-1(3)7(4,5)6;;;/h(H,2,3)(H2,4,5,6);;;/q;3*+1/p-3
SMILES [Na+].[Na+].[Na+].[O-]C(=O)P([O-])([O-])=O
Roles Classification
Biological Role(s): antiviral drug
A substance used in the prophylaxis or therapy of virus diseases.
Application(s): antiviral drug
A substance used in the prophylaxis or therapy of virus diseases.
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ChEBI Ontology
Outgoing trisodium phosphonoformate (CHEBI:141644) has part phosphonatoformate (CHEBI:60268)
trisodium phosphonoformate (CHEBI:141644) has role antiviral drug (CHEBI:36044)
trisodium phosphonoformate (CHEBI:141644) is a one-carbon compound (CHEBI:64708)
trisodium phosphonoformate (CHEBI:141644) is a organic sodium salt (CHEBI:38700)
Incoming trisodium phosphonoformate hexahydrate (CHEBI:60269) has part trisodium phosphonoformate (CHEBI:141644)
INNs Sources
foscarnet sodique ChemIDplus
foscarnet sodium KEGG DRUG
foscarneto sodico ChemIDplus
foscarnetum natricum ChemIDplus
Synonyms Sources
foscarnet sodium ChEMBL
trisodium carboxyphosphate ChemIDplus
trisodium carboxyphosphate (anhydrous) ChEBI
trisodium dioxidophosphinecarboxylate oxide ChEMBL
trisodium phosphonoformate ChEMBL
trisodium phosphonoformate (anhydrous) ChEBI
Manual Xrefs Databases
DB00529 DrugBank
View more database links
Registry Numbers Types Sources
63585-09-1 CAS Registry Number ChemIDplus
63585-09-1 CAS Registry Number KEGG DRUG
Last Modified
06 March 2017