CHEBI:140266 - 16,17(S)-dihydroxy-(7Z,10Z,13E,14E,19Z)-docosapentaenoic acid

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ChEBI Name 16,17(S)-dihydroxy-(7Z,10Z,13E,14E,19Z)-docosapentaenoic acid
ChEBI ID CHEBI:140266
ChEBI ASCII Name 16,17(S)-dihydroxy-(7Z,10Z,13E,14E,19Z)-docosapentaenoic acid
Definition A dihydroxydocosapentaenoic acid (DiHDPE) that is (7Z,10Z,13E,14E,19Z)-docosapentaenoic acid carrying two hydroxy substituents at the 16 and 17-S positions. It is an intermediate of specialised proresolving mediators.
Stars This entity has been manually annotated by the ChEBI Team.
Submitter Bijay
Supplier Information
Download Molfile XML SDF
Formula C22H34O4
Net Charge 0
Average Mass 362.504
Monoisotopic Mass 362.24571
InChI InChI=1S/C22H34O4/c1-2-3-14-17-20(23)21(24)18-15-12-10-8-6-4-5-7-9-11-13-16-19-22(25)26/h3,5-8,10,12,14-15,18,20-21,23-24H,2,4,9,11,13,16-17,19H2,1H3,(H,25,26)/b7-5-,8-6-,12-10+,14-3-,18-15+/t20-,21?/m0/s1
InChIKey HRNHRTOXACGZNE-KXMOHCNRSA-N
SMILES C(\C([C@H](C/C=C\CC)O)O)=C/C=C/C=C\C/C=C\CCCCCC(=O)O
Roles Classification
Chemical Role(s): Bronsted acid
A molecular entity capable of donating a hydron to an acceptor (Bronsted base).
(via oxoacid )
Biological Role(s): human xenobiotic metabolite
Any human metabolite produced by metabolism of a xenobiotic compound in humans.
specialised pro-resolving mediator
A class of cell signaling molecules enzymatically derived from n-3 long chain polyunsaturated fatty acids that have important roles in orchestrating the resolution of tissue inflammation.
metabolite
Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites.
(via DiHDPE )
Application(s): specialised pro-resolving mediator
A class of cell signaling molecules enzymatically derived from n-3 long chain polyunsaturated fatty acids that have important roles in orchestrating the resolution of tissue inflammation.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing 16,17(S)-dihydroxy-(7Z,10Z,13E,14E,19Z)-docosapentaenoic acid (CHEBI:140266) has role human xenobiotic metabolite (CHEBI:76967)
16,17(S)-dihydroxy-(7Z,10Z,13E,14E,19Z)-docosapentaenoic acid (CHEBI:140266) has role specialised pro-resolving mediator (CHEBI:140399)
16,17(S)-dihydroxy-(7Z,10Z,13E,14E,19Z)-docosapentaenoic acid (CHEBI:140266) is a DiHDPE (CHEBI:72656)
16,17(S)-dihydroxy-(7Z,10Z,13E,14E,19Z)-docosapentaenoic acid (CHEBI:140266) is conjugate acid of 16,17(S)-dihydroxy-(7Z,10Z,13E,14E,19Z)-docosapentaenoate (CHEBI:140406)
Incoming 16,17(S)-dihydroxy-(7Z,10Z,13E,14E,19Z)-docosapentaenoate (CHEBI:140406) is conjugate base of 16,17(S)-dihydroxy-(7Z,10Z,13E,14E,19Z)-docosapentaenoic acid (CHEBI:140266)
IUPAC Name
(7Z,10Z,12E,14E,17S,19Z)-16,17-dihydroxydocosa-7,10,12,14,19-pentaenoic acid
Synonyms Sources
(7Z,10Z,12E,14E,17S,19Z)-16,17-dihydroxydocosapentaenoic acid ChEBI
(PD)2n-3 DPA ChEBI
16,17(S)-dihydroxy-7Z,10Z,13E,14E,19Z-docosapentaenoic acid ChEBI
16,17(S)-dihydroxy-ω3-docosapentaenoic acid ChEBI
16,17(S)-dihydroxy-omega3-docosapentaenoic acid ChEBI
PD2n-3 DPA SUBMITTER
protectin D2n-3 DPA ChEBI
Registry Number Type Source
31878852 Reaxys Registry Number Reaxys
Citations Waiting for Citations Types Sources
23736886 PubMed citation Europe PMC
28408222 PubMed citation Europe PMC
Last Modified
12 March 2018