CHEBI:135813 - flomoxef

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name flomoxef
Definition A second-generation oxacephem antibiotic in which the oxazine ring is substituted at C-3 with a hydroxyethyl-substituted tetrazolylthiomethyl group and the azetidinone ring carries 7α-methoxy and 7β-{2-[(difluoromethyl)thiomethyl]acetamido} substituents.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
Download Molfile XML SDF
Wikipedia License
Waiting for wikipedia content
Read full article at Wikipedia
Formula C15H18F2N6O7S2
Net Charge 0
Average Mass 496.469
Monoisotopic Mass 496.06465
InChI InChI=1S/C15H18F2N6O7S2/c1-29-15(18-8(25)6-31-13(16)17)11(28)23-9(10(26)27)7(4-30-12(15)23)5-32-14-19-20-21-22(14)2-3-24/h12-13,24H,2-6H2,1H3,(H,18,25)(H,26,27)/t12-,15+/m1/s1
SMILES N(C(CSC(F)F)=O)[C@@]1(OC)[C@@]2(N(C1=O)C(=C(CO2)CSC=3N(CCO)N=NN3)C(=O)O)[H]
Roles Classification
Chemical Role(s): Bronsted acid
A molecular entity capable of donating a hydron to an acceptor (Bronsted base).
(via oxoacid )
Biological Role(s): antibacterial drug
A drug used to treat or prevent bacterial infections.
antimicrobial agent
A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans.
(via heterocyclic antibiotic )
Application(s): antibacterial drug
A drug used to treat or prevent bacterial infections.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing flomoxef (CHEBI:135813) has role antibacterial drug (CHEBI:36047)
flomoxef (CHEBI:135813) is a N-acyl-amino acid (CHEBI:51569)
flomoxef (CHEBI:135813) is a organonitrogen heterocyclic antibiotic (CHEBI:25558)
flomoxef (CHEBI:135813) is a oxacephem (CHEBI:55506)
(6R,7R)-7-{2-[(difluoromethyl)sulfanyl]acetamido}-3-({[1-(2-hydroxyethyl)-1H-tetrazol-5-yl]sulfanyl}methyl)-7-methoxy-8-oxo-5-oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
INNs Sources
flomoxef WHO MedNet
flomoxef WHO MedNet
flomoxef ChemIDplus
flomoxefum WHO MedNet
Synonym Source
Manual Xrefs Databases
1179 DrugCentral
DB11935 DrugBank
Flomoxef Wikipedia
View more database links
Registry Numbers Types Sources
6993219 Reaxys Registry Number Reaxys
99665-00-6 CAS Registry Number ChemIDplus
99665-00-6 CAS Registry Number DrugCentral
Citations Waiting for Citations Types Sources
12803802 PubMed citation Europe PMC
18606583 PubMed citation Europe PMC
25694055 PubMed citation Europe PMC
26100708 PubMed citation Europe PMC
26387064 PubMed citation Europe PMC
28543395 PubMed citation Europe PMC
29017833 PubMed citation Europe PMC
Last Modified
14 March 2018