CHEBI:135813 - flomoxef

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ChEBI Name flomoxef
ChEBI ID CHEBI:135813
Definition A second-generation oxacephem antibiotic in which the oxazine ring is substituted at C-3 with a hydroxyethyl-substituted tetrazolylthiomethyl group and the azetidinone ring carries 7α-methoxy and 7β-{2-[(difluoromethyl)thiomethyl]acetamido} substituents.
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C15H18F2N6O7S2
Net Charge 0
Average Mass 496.469
Monoisotopic Mass 496.06465
InChI InChI=1S/C15H18F2N6O7S2/c1-29-15(18-8(25)6-31-13(16)17)11(28)23-9(10(26)27)7(4-30-12(15)23)5-32-14-19-20-21-22(14)2-3-24/h12-13,24H,2-6H2,1H3,(H,18,25)(H,26,27)/t12-,15+/m1/s1
InChIKey UHRBTBZOWWGKMK-DOMZBBRYSA-N
SMILES N(C(CSC(F)F)=O)[C@@]1(OC)[C@@]2(N(C1=O)C(=C(CO2)CSC=3N(CCO)N=NN3)C(=O)O)[H]
Roles Classification
Chemical Role(s): Bronsted acid
A molecular entity capable of donating a hydron to an acceptor (Bronsted base).
(via oxoacid )
Biological Role(s): antibacterial drug
A drug used to treat or prevent bacterial infections.
antimicrobial agent
A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans.
(via heterocyclic antibiotic )
Application(s): antibacterial drug
A drug used to treat or prevent bacterial infections.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing flomoxef (CHEBI:135813) has role antibacterial drug (CHEBI:36047)
flomoxef (CHEBI:135813) is a N-acyl-amino acid (CHEBI:51569)
flomoxef (CHEBI:135813) is a organonitrogen heterocyclic antibiotic (CHEBI:25558)
flomoxef (CHEBI:135813) is a oxacephem (CHEBI:55506)
IUPAC Name
(6R,7R)-7-{2-[(difluoromethyl)sulfanyl]acetamido}-3-({[1-(2-hydroxyethyl)-1H-tetrazol-5-yl]sulfanyl}methyl)-7-methoxy-8-oxo-5-oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
INNs Sources
flomoxef WHO MedNet
flomoxef WHO MedNet
flomoxef ChemIDplus
flomoxefum WHO MedNet
Synonym Source
FMOX ChEBI
Manual Xrefs Databases
1179 DrugCentral
D07963 KEGG DRUG
DB11935 DrugBank
Flomoxef Wikipedia
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Registry Numbers Types Sources
6993219 Reaxys Registry Number Reaxys
99665-00-6 CAS Registry Number ChemIDplus
99665-00-6 CAS Registry Number DrugCentral
Citations Waiting for Citations Types Sources
12803802 PubMed citation Europe PMC
18606583 PubMed citation Europe PMC
25694055 PubMed citation Europe PMC
26100708 PubMed citation Europe PMC
26387064 PubMed citation Europe PMC
28543395 PubMed citation Europe PMC
29017833 PubMed citation Europe PMC
Last Modified
14 March 2018