CHEBI:135538 - propyphenazone

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ChEBI Name propyphenazone
ChEBI ID CHEBI:135538
Definition A pyrazolone derivative that is antipyrine substituted at C-4 by an isopropyl group.
Stars This entity has been manually annotated by the ChEBI Team.
Secondary ChEBI IDs CHEBI:31732
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Formula C14H18N2O
Net Charge 0
Average Mass 230.30550
Monoisotopic Mass 230.142
InChI InChI=1S/C14H18N2O/c1-10(2)13-11(3)15(4)16(14(13)17)12-8-6-5-7-9-12/h5-10H,1-4H3
InChIKey PXWLVJLKJGVOKE-UHFFFAOYSA-N
SMILES CC(C)c1c(C)n(C)n(-c2ccccc2)c1=O
Roles Classification
Biological Role(s): non-narcotic analgesic
A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors.
Application(s): non-steroidal anti-inflammatory drug
An anti-inflammatory drug that is not a steroid. In addition to anti-inflammatory actions, non-steroidal anti-inflammatory drugs have analgesic, antipyretic, and platelet-inhibitory actions. They act by blocking the synthesis of prostaglandins by inhibiting cyclooxygenase, which converts arachidonic acid to cyclic endoperoxides, precursors of prostaglandins.
non-narcotic analgesic
A drug that has principally analgesic, antipyretic and anti-inflammatory actions. Non-narcotic analgesics do not bind to opioid receptors.
peripheral nervous system drug
A drug that acts principally at one or more sites within the peripheral neuroeffector systems, the autonomic system, and motor nerve-skeletal system.
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ChEBI Ontology
Outgoing propyphenazone (CHEBI:135538) has functional parent antipyrine (CHEBI:31225)
propyphenazone (CHEBI:135538) has role non-narcotic analgesic (CHEBI:35481)
propyphenazone (CHEBI:135538) has role non-steroidal anti-inflammatory drug (CHEBI:35475)
propyphenazone (CHEBI:135538) has role peripheral nervous system drug (CHEBI:49110)
propyphenazone (CHEBI:135538) is a pyrazolone (CHEBI:83328)
IUPAC Name
1,5-dimethyl-2-phenyl-4-(propan-2-yl)-1,2-dihydro-3H-pyrazol-3-one
INNs Sources
propifenazona ChemIDplus
propyphenazone ChemIDplus
propyphenazonum ChemIDplus
Synonyms Sources
1-Phenyl-2,3-dimethyl-4-isopropyl-3-pyrazolin-5-one ChemIDplus
1-Phenyl-2,3-dimethyl-4-isopropylpyrazol-5-one ChemIDplus
4-Isopropyl-1,5-dimethyl-2-phenyl-1,2-dihydro-pyrazol-3-one ChEMBL
4-Isopropylantipyrine ChemIDplus
Isopropylantipyrine ChemIDplus
Isopropylphenazone ChemIDplus
Manual Xrefs Databases
2309 DrugCentral
D01380 KEGG DRUG
Propyphenazone Wikipedia
View more database links
Registry Numbers Types Sources
204533 Beilstein Registry Number Beilstein
204533 Reaxys Registry Number Reaxys
479-92-5 CAS Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
12097837 PubMed citation Europe PMC
21684706 PubMed citation Europe PMC
23277879 PubMed citation Europe PMC
25221653 PubMed citation Europe PMC
26319751 PubMed citation Europe PMC
3425858 PubMed citation Europe PMC
Last Modified
06 March 2017