CHEBI:134269 - 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)pentan-1-one

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ChEBI Name 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)pentan-1-one
Definition A differentiation-inducing factor that is pentaphenone bearing two chloro substituents at positions 3 and 5, two hydroxy substituents at positions 2 and 6 as well as a single methoxy substituent at position 4. A secreted, chlorinated molecule that controls cell fate during development of Dictyostelium cells.
Stars This entity has been manually annotated by the ChEBI Team.
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Formula C12H14Cl2O4
Net Charge 0
Average Mass 293.143
Monoisotopic Mass 292.02691
InChI InChI=1S/C12H14Cl2O4/c1-3-4-5-6(15)7-10(16)8(13)12(18-2)9(14)11(7)17/h16-17H,3-5H2,1-2H3
Roles Classification
Biological Role(s): eukaryotic metabolite
Any metabolite produced during a metabolic reaction in eukaryotes, the taxon that include members of the fungi, plantae and animalia kingdoms.
(via differentiation-inducing factor )
signalling molecule
A molecular messenger in which the molecule is specifically involved in transmitting information between cells. Such molecules are released from the cell sending the signal, cross over the gap between cells by diffusion, and interact with specific receptors in another cell, triggering a response in that cell by activating a series of enzyme controlled reactions which lead to changes inside the cell.
A small molecule which increases (activator) or decreases (inhibitor) the activity of an (allosteric) enzyme by binding to the enzyme at the regulatory site (which is different from the substrate-binding catalytic site).
(via differentiation-inducing factor )
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ChEBI Ontology
Outgoing 1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)pentan-1-one (CHEBI:134269) has role eukaryotic metabolite (CHEBI:75763)
1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)pentan-1-one (CHEBI:134269) has role signalling molecule (CHEBI:62488)
1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)pentan-1-one (CHEBI:134269) is a dichlorobenzene (CHEBI:23697)
1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)pentan-1-one (CHEBI:134269) is a differentiation-inducing factor (CHEBI:64672)
1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)pentan-1-one (CHEBI:134269) is a monomethoxybenzene (CHEBI:25235)
1-(3,5-dichloro-2,6-dihydroxy-4-methoxyphenyl)pentan-1-one (CHEBI:134269) is a resorcinols (CHEBI:33572)
Synonyms Sources
1-(3,5-Dichloro-2,6-dihydroxy-4-methoxyphenyl-)-1-pentanone ChemIDplus
Dif-2 (dictyostelium) ChemIDplus
differentiation-inducing factor 2 ChEBI
differentiation-inducing factor-2 ChEBI
Manual Xref Database
Differentiation-inducing_factor Wikipedia
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Registry Numbers Types Sources
10181236 Reaxys Registry Number Reaxys
113411-16-8 CAS Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
1850369 PubMed citation Europe PMC
19684855 PubMed citation Europe PMC
21258165 PubMed citation Europe PMC
26688830 PubMed citation Europe PMC
26919666 PubMed citation Europe PMC
3355503 PubMed citation Europe PMC
Last Modified
24 January 2017