CHEBI:132768 - angelol-J

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ChEBI Name angelol-J
Definition A member of the class of coumarins that is 7-methoxycoumarin in which the hydrogen at position 6 has been replaced by a 1-ethoxy-2,3-dihydroxy-3-methylbutyl group (the R,R stereoisomer). Originally isolated from the roots of Angelica pubescens, angelol J shows strong inhibitory effects on human platelet aggregation.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Formula C17H22O6
Net Charge 0
Average Mass 322.354
Monoisotopic Mass 322.14164
InChI InChI=1S/C17H22O6/c1-5-22-15(16(19)17(2,3)20)11-8-10-6-7-14(18)23-12(10)9-13(11)21-4/h6-9,15-16,19-20H,5H2,1-4H3/t15-,16-/m1/s1
SMILES C=1C(OC2=C(C1)C=C([C@@H](OCC)[C@@H](O)C(O)(C)C)C(=C2)OC)=O
Metabolite of Species Details
Angelica pubescens (NCBI:txid312530) Found in root (BTO:0001188). EtOAc-soluble fraction See: PubMed
Roles Classification
Biological Role(s): plant metabolite
Any eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms.
Application(s): platelet aggregation inhibitor
A drug or agent which antagonizes or impairs any mechanism leading to blood platelet aggregation, whether during the phases of activation and shape change or following the dense-granule release reaction and stimulation of the prostaglandin-thromboxane system.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing angelol-J (CHEBI:132768) has role plant metabolite (CHEBI:76924)
angelol-J (CHEBI:132768) has role platelet aggregation inhibitor (CHEBI:50427)
angelol-J (CHEBI:132768) is a aromatic ether (CHEBI:35618)
angelol-J (CHEBI:132768) is a coumarins (CHEBI:23403)
angelol-J (CHEBI:132768) is a diol (CHEBI:23824)
Synonym Source
angelol J ChEBI
Registry Number Type Source
7387555 Reaxys Registry Number Reaxys
Citation Waiting for Citations Type Source
17238102 PubMed citation Europe PMC
Last Modified
20 July 2016