CHEBI:131726 - brodimoprim

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ChEBI Name brodimoprim
ChEBI ID CHEBI:131726
Definition An aminopyrimidine that is 2,4-diaminopyrimidine in which the hydrogen at position 5 has been replaced by a 4-bromo-3,5-dimethoxybenzyl group.
Stars This entity has been manually annotated by the ChEBI Team.
Submitter Kevin
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Formula C13H15BrN4O2
Net Charge 0
Average Mass 339.188
Monoisotopic Mass 338.038
InChI InChI=1S/C13H15BrN4O2/c1-19-9-4-7(5-10(20-2)11(9)14)3-8-6-17-13(16)18-12(8)15/h4-6H,3H2,1-2H3,(H4,15,16,17,18)
InChIKey BFCRRLMMHNLSCP-UHFFFAOYSA-N
SMILES C=1(C=C(C(=C(C1)OC)Br)OC)CC=2C(=NC(=NC2)N)N
Roles Classification
Chemical Role(s): Bronsted base
A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
(via organic amino compound )
Biological Role(s): EC 1.5.1.3 (dihydrofolate reductase) inhibitor
An EC 1.5.1.* (oxidoreductase acting on donor CH-NH group, NAD+ or NADP+ as acceptor) inhibitor that interferes with the action of dihydrofolate reductase (EC 1.5.1.3).
antibacterial drug
A drug used to treat or prevent bacterial infections.
Application(s): antiinfective agent
A substance used in the prophylaxis or therapy of infectious diseases.
antibacterial drug
A drug used to treat or prevent bacterial infections.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing brodimoprim (CHEBI:131726) has role antibacterial drug (CHEBI:36047)
brodimoprim (CHEBI:131726) has role antiinfective agent (CHEBI:35441)
brodimoprim (CHEBI:131726) has role EC 1.5.1.3 (dihydrofolate reductase) inhibitor (CHEBI:50683)
brodimoprim (CHEBI:131726) is a aminopyrimidine (CHEBI:38338)
brodimoprim (CHEBI:131726) is a bromobenzenes (CHEBI:37149)
brodimoprim (CHEBI:131726) is a methoxybenzenes (CHEBI:51683)
IUPAC Name
5-(4-bromo-3,5-dimethoxybenzyl)pyrimidine-2,4-diamine
INNs Sources
brodimoprim WHO MedNet
brodimoprima WHO MedNet
brodimoprime WHO MedNet
brodimoprimum WHO MedNet
Synonyms Sources
2,4-diamino-5-(4-bromo-3,5-dimethoxybenzyl)pyrimidine ChemIDplus
Ro 10-5970 ChemIDplus
Ro 105970 ChemIDplus
Manual Xrefs Databases
398 DrugCentral
Brodimoprim Wikipedia
D07238 KEGG DRUG
View more database links
Registry Numbers Types Sources
56518-41-3 CAS Registry Number KEGG DRUG
56518-41-3 CAS Registry Number ChemIDplus
760113 Reaxys Registry Number Reaxys
Citations Waiting for Citations Types Sources
6363003 PubMed citation Europe PMC
7164825 PubMed citation Europe PMC
7562018 PubMed citation Europe PMC
8195832 PubMed citation Europe PMC
8195840 PubMed citation Europe PMC
8195841 PubMed citation Europe PMC
8195848 PubMed citation Europe PMC
Last Modified
22 February 2017