CHEBI:131723 - sulfathiourea

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ChEBI Name sulfathiourea
ChEBI ID CHEBI:131723
Definition A substituted aniline that is thiourea in which one of the hydrogens has been replaced by a (p-aminophenyl)sulfonyl group.
Stars This entity has been manually annotated by the ChEBI Team.
Submitter Kevin
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Formula C7H9N3O2S2
Net Charge 0
Average Mass 231.298
Monoisotopic Mass 231.014
InChI InChI=1S/C7H9N3O2S2/c8-5-1-3-6(4-2-5)14(11,12)10-7(9)13/h1-4H,8H2,(H3,9,10,13)
InChIKey UEMLYRZWLVXWRU-UHFFFAOYSA-N
SMILES C=1(C=CC(=CC1)N)S(NC(N)=S)(=O)=O
Roles Classification
Chemical Role(s): Bronsted base
A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
(via organic amino compound )
Biological Role(s): EC 2.5.1.15 (dihydropteroate synthase) inhibitor
An EC 2.5.1.* (non-methyl-alkyl or aryl transferase) inhibitor that interferes with the action of dihydropteroate synthase (EC 2.5.1.15), an enzyme that catalyzes the formation of dihydropteroate from p-aminobenzoic acid and dihydropteridine-hydroxymethyl-pyrophosphate.
antibacterial drug
A drug used to treat or prevent bacterial infections.
antimicrobial agent
A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans.
(via sulfonamide antibiotic )
Application(s): antibacterial drug
A drug used to treat or prevent bacterial infections.
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ChEBI Ontology
Outgoing sulfathiourea (CHEBI:131723) has functional parent sulfanilamide (CHEBI:45373)
sulfathiourea (CHEBI:131723) has role antibacterial drug (CHEBI:36047)
sulfathiourea (CHEBI:131723) has role EC 2.5.1.15 (dihydropteroate synthase) inhibitor (CHEBI:50502)
sulfathiourea (CHEBI:131723) is a substituted aniline (CHEBI:48975)
sulfathiourea (CHEBI:131723) is a sulfonamide antibiotic (CHEBI:87228)
sulfathiourea (CHEBI:131723) is a thioureas (CHEBI:51276)
IUPAC Name
4-amino-N-carbamothioylbenzenesulfonamide
INNs Sources
sulfathiourea WHO MedNet
sulfathiourea WHO MedNet
sulfathiourée WHO MedNet
sulfatiourea WHO MedNet
Synonyms Sources
1-sulfanilyl-2-thiourea ChEBI
2-Sulfanilamidothiokarbamid ChemIDplus
4-amino-N-(aminothioxomethyl)benzenesulfonamide ChemIDplus
p-aminobenzenesulfonylthiourea ChemIDplus
p-aminophenylsulfonylthiourea ChemIDplus
R.P. 2255 ChemIDplus
RP 2255 ChemIDplus
RP-2255 ChEBI
sulfathiocarbamide ChemIDplus
sulphathiourea KEGG DRUG
Brand Names Sources
Badional ChemIDplus
Fontamide ChemIDplus
Manual Xrefs Databases
3567 DrugCentral
D07239 KEGG DRUG
Sulfathiourea Wikipedia
US2332906 Patent
View more database links
Registry Numbers Types Sources
2696478 Reaxys Registry Number Reaxys
515-49-1 CAS Registry Number KEGG DRUG
515-49-1 CAS Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
13137202 PubMed citation Europe PMC
15198720 PubMed citation Europe PMC
1911981 PubMed citation Europe PMC
21024878 PubMed citation Europe PMC
24544024 PubMed citation Europe PMC
7486915 PubMed citation Europe PMC
Last Modified
22 February 2017