CHEBI:131715 - rosoxacin

Main ChEBI Ontology Automatic Xrefs Reactions Pathways Models
ChEBI Name rosoxacin
ChEBI ID CHEBI:131715
Definition A quinolinemonocarboxylic acid that is 1,4-dihydroquinoline-3-carboxylic acid that is substituted by an ethyl group at position 1 and by a pyridin-4-yl group at position 7. An antibacterial drug, active against Neisseria gonorrhoeae, it has been used for treating urinary tract infections and certain sexually transmitted diseases.
Stars This entity has been manually annotated by the ChEBI Team.
Submitter Kevin
Supplier Information
Download Molfile XML SDF
more structures >>
Formula C17H14N2O3
Net Charge 0
Average Mass 294.305
Monoisotopic Mass 294.100
InChI InChI=1S/C17H14N2O3/c1-2-19-10-14(17(21)22)16(20)13-4-3-12(9-15(13)19)11-5-7-18-8-6-11/h3-10H,2H2,1H3,(H,21,22)
InChIKey XBPZXDSZHPDXQU-UHFFFAOYSA-N
SMILES C1(C=2C=CC(=CC2N(C=C1C(=O)O)CC)C3=CC=NC=C3)=O
Roles Classification
Chemical Role(s): Bronsted acid
A molecular entity capable of donating a hydron to an acceptor (Bronsted base).
(via oxoacid )
Biological Role(s): antibacterial drug
A drug used to treat or prevent bacterial infections.
antimicrobial agent
A substance that kills or slows the growth of microorganisms, including bacteria, viruses, fungi and protozoans.
(via quinolone antibiotic )
(via heterocyclic antibiotic )
Application(s): antibacterial drug
A drug used to treat or prevent bacterial infections.
antiinfective agent
A substance used in the prophylaxis or therapy of infectious diseases.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing rosoxacin (CHEBI:131715) has role antibacterial drug (CHEBI:36047)
rosoxacin (CHEBI:131715) has role antiinfective agent (CHEBI:35441)
rosoxacin (CHEBI:131715) is a pyridines (CHEBI:26421)
rosoxacin (CHEBI:131715) is a quinolinemonocarboxylic acid (CHEBI:26512)
rosoxacin (CHEBI:131715) is a quinolone antibiotic (CHEBI:86324)
IUPAC Name
1-ethyl-4-oxo-7-(pyridin-4-yl)-1,4-dihydroquinoline-3-carboxylic acid
INNs Sources
rosoxacin WHO MedNet
rosoxacina WHO MedNet
rosoxacine WHO MedNet
rosoxacinum WHO MedNet
Synonyms Sources
1-ethyl-1,4-dihydro-4-oxo-7-(4-pyridyl)-3-quinolinecarboxylic acid ChemIDplus
Win 35,213 ChemIDplus
Win 35213 ChEBI
Win-35,213 ChEBI
Brand Names Sources
Eradacil ChemIDplus
Roxadyl SUBMITTER
Manual Xrefs Databases
83 DrugCentral
D02305 KEGG DRUG
DB00817 DrugBank
DE2224090 Patent
HMDB0014955 HMDB
US3753993 Patent
US3907808 Patent
View more database links
Registry Numbers Types Sources
40034-42-2 CAS Registry Number ChemIDplus
40034-42-2 CAS Registry Number KEGG DRUG
758231 Reaxys Registry Number Reaxys
Citations Waiting for Citations Types Sources
17804284 PubMed citation Europe PMC
1966732 PubMed citation Europe PMC
2934234 PubMed citation Europe PMC
2958947 PubMed citation Europe PMC
3122279 PubMed citation Europe PMC
3489439 PubMed citation Europe PMC
6142282 PubMed citation Europe PMC
6241772 PubMed citation Europe PMC
Last Modified
22 February 2017