CHEBI:123115 - diaveridine

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ChEBI Name diaveridine
Definition An aminopyrimidine in which the pyrimidine ring carries amino substituents at C-2 and C-4 and a 3,4-dimethoxybenzyl group at C-5. A folic acid antagonist, it is used as a synergist with sulfonamides against the parasitic Eimeria species.
Stars This entity has been manually annotated by the ChEBI Team.
Supplier Information
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Formula C13H16N4O2
Net Charge 0
Average Mass 260.29170
Monoisotopic Mass 260.12733
InChI InChI=1S/C13H16N4O2/c1-18-10-4-3-8(6-11(10)19-2)5-9-7-16-13(15)17-12(9)14/h3-4,6-7H,5H2,1-2H3,(H4,14,15,16,17)
SMILES COc1ccc(Cc2cnc(N)nc2N)cc1OC
Roles Classification
Chemical Role(s): Bronsted base
A molecular entity capable of accepting a hydron from a donor (Bronsted acid).
(via organic amino compound )
Biological Role(s): drug allergen
Any drug which causes the onset of an allergic reaction.
Application(s): antiparasitic agent
A substance used to treat or prevent parasitic infections.
drug allergen
Any drug which causes the onset of an allergic reaction.
View more via ChEBI Ontology
ChEBI Ontology
Outgoing diaveridine (CHEBI:123115) has role antiparasitic agent (CHEBI:35442)
diaveridine (CHEBI:123115) has role drug allergen (CHEBI:88188)
diaveridine (CHEBI:123115) is a aminopyrimidine (CHEBI:38338)
INNs Sources
diaveridina ChemIDplus
diaveridine ChemIDplus
diaveridinum ChemIDplus
Synonyms Sources
2,4-Diamino-5-(3,4-dimethoxybenzyl)pyrimidine ChemIDplus
2,4-Diamino-5-veratrylpyrimidine ChemIDplus
5-((3,4-Dimethoxyphenyl)methyl)-2,4-pyrimidinediamine ChemIDplus
5-(3,4-Dimethoxy-benzyl)-pyrimidine-2,4-diamine ChEMBL
Diaveridin ChemIDplus
Manual Xrefs Databases
US2624732 Patent
US3341541 Patent
View more database links
Registry Numbers Types Sources
0258464 Beilstein Registry Number Beilstein
258464 Reaxys Registry Number Reaxys
5355-16-8 CAS Registry Number KEGG DRUG
5355-16-8 CAS Registry Number ChemIDplus
Citations Waiting for Citations Types Sources
21781790 PubMed citation Europe PMC
2327254 PubMed citation Europe PMC
24999617 PubMed citation Europe PMC
3377143 PubMed citation Europe PMC
4982548 PubMed citation Europe PMC
8911701 PubMed citation Europe PMC
Last Modified
04 March 2019